LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Enhancement of Annexin V in response to combination of epigallocatechin gallate and quercetin as a potent arrest the cell cycle of colorectal cancer

Al-Ghamdi, Maryam A; AL-Enazy, A; Huwait, E A; Albukhari, A; Harakeh, S; Moselhy, Said S.

Braz. j. biol; 83 (), 2023

Abstract Colorectal cancer (CRC) is one of the most common cancers leading to comorbidities and mortalities globally. The rational of current study was to evaluate the combined epigallocatechin gallate and quercetin as a potent antitumor agent as commentary agent for therapeutic protocol. The present stu...

Anexina A5, Catequina/análogos & derivados, Catequina/farmacología, Ciclo Celular, Línea Celular Tumoral, Proliferación Celular, Neoplasias Colorrectales/tratamiento farmacológico, Quercetina/farmacología

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Anti-annexin V autoantibodies and vascular abnormalities in systemic sclerosis: a longitudinal study

Horimoto, Alex Magno Coelho; Jesus, Laize Guerreiro de; Souza, Albert Schiaveto de; Rodrigues, Silvia Helena; Kayser, Cristiane.

Adv Rheumatol; 60 (), 2020

Abstract Background: Annexins are a group of conserved proteins which exert several regulatory functions on various cellular activities. Increased frequency and levels of antibodies against annexin V have already been observed in several autoimmune diseases including systemic sclerosis (SSc), but their ...

Esclerodermia Sistémica/fisiopatología, Anexina A5/sangre, Inmunoglobulina G/sangre, Biomarcadores/análisis, Estudios Transversales/instrumentación, Angioscopía Microscópica/instrumentación

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Serum Annexin V and Anti-Annexin V levels and their relationship with metabolic parameters in patients with type 2 diabetes

Bilgir, Oktay; Vural, Huseyin Afsin; Bilgir, Ferda; Akan, Ozden Yildirim; Demir, Ismail.

Rev. Assoc. Med. Bras. (1992, Impr.); 65 (8), 2019

SUMMARY BACKGROUND We investigated the serum annexin V and anti-annexin V levels and their relationship with metabolic parameters in patients recently diagnosed type 2 diabetic. METHODS A total of 143 patients recently diagnosed type 2 diabetes and 133 control subjects were included in the study. Bod...

Anexina A5/sangre, Anexina A5/inmunología, Anexina A5/metabolismo, Autoanticuerpos/sangre, Índice de Masa Corporal, Grosor Intima-Media Carotídeo, Estudios de Casos y Controles, Estudios Transversales, Diabetes Mellitus Tipo 2/sangre, Diabetes Mellitus Tipo 2/metabolismo, Homeostasis, Persona de Mediana Edad

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Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cells

Doan, Chung Chinh; Le, Long Thanh; Hoang, Son Nghia; Do, Si Minh; Van Le, Dong.

Biol. Res; 47 (), 2014

BACKGROUND: Vascular endothelial growth factor (VEGF) is involved in the growth of new blood vessels that feed tumors and kinesin spindle protein (KSP) plays a critical role in mitosis involving in cell proliferation. Simultaneous silencing of VEGF and KSP, an attractive and viable approach in cancer, le...

Apoptosis/genética, Proliferación Celular/genética, Silenciador del Gen, Cinesinas/genética, ARN Interferente Pequeño/genética, Factor A de Crecimiento Endotelial Vascular/genética, Ciclina D1/metabolismo, Inhibidores de Cisteína Proteinasa/metabolismo, Células Endoteliales de la Vena Umbilical Humana/metabolismo, Proteínas Inhibidoras de la Apoptosis/metabolismo, Cinesinas/metabolismo, Mitosis/genética, Factor A de Crecimiento Endotelial Vascular/metabolismo, Proteínas de Transporte Vesicular/metabolismo, Anexina A5, Western Blotting, Línea Celular Tumoral, Movimiento Celular, Regulación hacia Abajo, Citometría de Flujo, Genes bcl-2, Reacción en Cadena en Tiempo Real de la Polimerasa, Survivin, Sales de Tetrazolio, Transfección

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