Genetic alterations in Ki-ras and Ha-ras genes in juvenile nasopharyngeal angiofibromas and head and neck cancer
Säo Paulo med. j; 117 (3), 1999
Context: Ras gene mutations have been associated to a wide range of human solid tumors. Members of the ras gene family (Ki-ras, Ha-ras and N-ras) are structurally related and code for a protein (p21) known to play an important role in the regulation of normal signal transduction and cell growth. The freq...
Codón/genética, Mutación/genética, Carcinoma de Células Escamosas/genética, Neoplasias Nasofaríngeas/genética, Neoplasias de Cabeza y Cuello/genética, Angiofibroma/genética, Genes ras, Reacción en Cadena de la Polimerasa, Polimorfismo Conformacional Retorcido-Simple, Northern Blotting, Anciano de 80 o más Años, ADN de Neoplasias/genética, ARN Neoplásico, Secuencia de Bases