ABSTRACT Objective: To observe the therapeutic effect of gentiopicroside, as the main component of Gentianaceae, on wounds in pressure injury (PI) model rats and explore its mechanism. Method: Male Sprague Dawley rats were randomly divided into control group, model group and gentiopicroside groups (50,...
An, Fangyu;
Yan, Chunlu;
Li, Jiajin;
Lv, Xueying;
Wang, Caixia;
Deng, Jie;
Shi, Biao;
Zhang, Jinlong;
Che, Wenxuan;
Zheng, Wenrui.
SUMMARY: The 12C6+ heavy ion beam irradiation can cause bystander effects. The inflammatory cytokines, endocrine hormones and apoptotic proteins may be involved in 12C6+ irradiation-induced bystander effects. This study characterized the protective effects and mechanisms of Huangqi decoction (HQD) agains...
Scutellaria baicalensis/química,
Medicamentos Herbarios Chinos,
Sustancias Protectoras/administración & dosificación,
Apoptosis/efectos de los fármacos,
Apoptosis/efectos de la radiación,
Iones Pesados/efectos adversos,
Factores Inmunológicos/antagonistas & inhibidores,
Hormona Liberadora de Corticotropina,
Sistema Endocrino/efectos de los fármacos,
Sistema Endocrino/efectos de la radiación,
Ratas Wistar,
Antígeno Nuclear de Célula en Proliferación,
Riñón/efectos de los fármacos,
Riñón/efectos de la radiación,
Encéfalo/efectos de los fármacos,
Encéfalo/efectos de la radiación,
Hormona Adrenocorticotrópica,
Ensayo de Inmunoadsorción Enzimática
SUMMARY: The present study investigated the possible protective effects of melatonin on Bleomycin, Cisplatin and etoposide (BEP) chemotherapy regimens using immunohistochemistry. Forty male Wistar rats were divided into four groups of ten as; group 1 as untreated control; group 2 as BEP group which recei...
Bleomicina/efectos adversos,
Cisplatino/efectos adversos,
Etopósido/efectos adversos,
Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos,
Melatonina/administración & dosificación,
Antioxidantes/administración & dosificación,
Apoptosis/efectos de los fármacos,
Inmunohistoquímica,
Ratas Wistar,
Sustancias Protectoras,
Antígeno Nuclear de Célula en Proliferación,
Enfermedades Pulmonares/prevención & control,
Enfermedades Pulmonares/inducido químicamente
SUMMARY: Acrylamide (AA) is a widely used chemical and an important monomer in various industrial and laboratory processes. In addition, AA is formed during processing of starchy food at high temperature. The aim of our study was to examine effects of subchronic AA treatment on adult rat liver using hist...
SUMMARY: GDM is linked with overexpression of inflammatory cytokines and increased oxidative stress, leading to endothelial dysfunction and vascular disorder. Weaimed to examine the expression of ADAMTS13 and PCNA in the placentas of gestational diabetes mellitus (GDM) patients to investigate the effects...
In the current study, the histological structure of the gallbladder of Alburnus tarichi (Güldenstädt, 1814) was investigated. Hematoxylin and eosin were used to stain the histological sections for routine examinations, in addition to using periodic acid Schiff (PAS) for the neutral mucins, aldehyde fuc...
ABSTRACT Objective To analyze the morphological and functional characteristics of primary macronodular adrenal hyperplasia (PMAH) nodules carrying or not carrying ARMC5 mutations and the consequences of the presence of mutations in terms of the pattern of macronodule composition and functional state. ...
Sebaceous tumors are common in dogs. These tumors include both benign and malignant lesions. Immunohistochemical evaluation of these tumors can aggregate information regarding the origin and degree of malignancy of the lesions. Focusing on this matter, sixty-one samples including normal skin and sebaceou...
Ethephon (Ethrel®) is an ethylene-based plant growth regulator that used in agriculture and it has direct and indirect effects on human health, direct effect via its inhalation during usage in agriculture and indirect effect through the diet (Fruits and vegetables) that is sprayed with it. The current s...
Abstract Objective To investigate the action of testosterone (T), isolated or associated with estradiol benzoate (EB), on the proliferation markers and apoptosis of breasts of ovariectomized rats. Methods A total of 48 castrated female Wistar rats were divided into 6 groups, and each of them were sub...
Apoptosis/efectos de los fármacos,
Biomarcadores/análisis,
Mama/citología,
Mama/patología,
Calcinosis/patología,
Caspasa 3/análisis,
Proliferación Celular/efectos de los fármacos,
Estradiol/análogos & derivados,
Estradiol/farmacología,
Ovariectomía,
Antígeno Nuclear de Célula en Proliferación/análisis,
Ratas Wistar,
Testosterona/farmacología
