Pine ( Pinus densiflora ) needle extract could promote the expression of PCNA and Ki-67 after partial hepatectomy in rat
Acta cir. bras; 34 (6), 2019
Abstract Purpose To investigate the effects of pine needle extract (PNE) on the expression of proliferating cell nuclear antigen (PCNA) and Ki-67 during liver regeneration induced by 70% partial hepatectomy (PH) in rat. Methods Forty-eight male rats (SD, 7 weeks) had surgery (70% PH). They were randoml...
Proliferación Celular, Hepatectomía/métodos, Antígeno Ki-67/efectos adversos, Antígeno Ki-67/metabolismo, Regeneración Hepática/efectos de los fármacos, Índice Mitótico, Pinus/química, Extractos Vegetales/farmacología, Antígeno Nuclear de Célula en Proliferación/efectos de los fármacos, Antígeno Nuclear de Célula en Proliferación/metabolismo, Ratas Sprague-Dawley, Factores de Tiempo