Purpose:
To evaluate fibrosis formation and number of macrophages in capsules formed around textured implants without and with mesh coverage.
Methods:
Fibrosis was analyzed through transforming growth factor-beta 1 (TGF-β1) immunomarker expression and the number of macrophages through CD68 percentage o...
Abstract Objective Preeclampsia (PE) is a pregnancy-specific syndrome characterized by abnormal levels of cytokines and angiogenic factors, playing a role in the disease development. The present study evaluated whether immunological markers are associated with the gestational age and with the disease s...
This study aimed to explore gene expression profiles that drive malignancy from low- to high-grade head and neck carcinomas (HNC), as well as to analyze their correlations with survival. Gene expressions and clinical data of HNC were downloaded from the Gene Expression Omnibus (GEO) repository. The signi...
Czeczko, Leticia Elizabeth Augustin;
Ribas, Carmen Australia Paredes Marcondes;
Czeczko, Nicolau Gregori;
Skare, Thelma Larocca;
Yamakawa, Camila Kienen;
Gionedis, Guilherme;
Vasconcelos, Cecilia;
Bremer, Fabiola Pabst;
Castoldi, Diogo Francesco;
Gasser, Martin;
Waaga-Gasser, Ana Maria.
ABSTRACT Background: CD133 and AXL have been described as cancer stem cell markers, and c-MYC as a key regulatory cellular mechanism in colorectal cancer (CRC). Aim: Evaluate the prognostic role of the biomarkers CD133, AXL and c-MYC and their association with clinicopathologic characteristics in colo...
SUMMARY: Meniscus tear is an important injury affecting the quality of life. This work is aimed to investigate the activity of CD68 and ADAMTS-5 in cells in synovial fluid in male and female patients with meniscal tear. In this study ,18 male and 22 female patients with meniscal tears were included. Loca...
SUMMARY: Acrylamide (ACR) is a cytotoxic and carcinogenic material. It is a product of a Maillard reaction during the cooking of many types of fried fast food, e.g. potato chip fries, and chicken nuggets. ACR has a severe toxic effect on different body organs. This study investigates the hepatotoxic effe...
Ácido Ascórbico/farmacología,
Silimarina/farmacología,
Acrilamida/toxicidad,
Hígado/efectos de los fármacos,
Hígado/metabolismo,
Hígado/patología,
Antígenos CD/análisis,
Actinas/análisis,
Inmunohistoquímica,
Células Estrelladas Hepáticas,
Hepatocitos
Abstract The aim of our study was to isolate populations of keratinocyte stem cells based on the expression of cell surface markers and to investigate whether the culture could affect their phenotype. keratinocytes from human oral mucosa were sorted based on the expression of the epithelial stem cell mar...
Citometría de Flujo/métodos,
Células Epiteliales/citología,
Separación Celular/métodos,
Técnicas de Cultivo de Célula/métodos,
Biomarcadores/análisis,
Antígenos CD/análisis,
Queratinocitos/citología,
Mucosa Bucal/citología,
Proteínas del Tejido Nervioso/análisis,
Fenotipo,
Receptores de Factor de Crecimiento Nervioso/análisis,
Receptores de Transferrina/análisis,
Reproducibilidad de los Resultados,
Células Madre/citología
Resumen Los pacientes con lepra lepromatosa que han recibido tratamiento durante años, usualmente requieren seguimiento con biopsias de piel para detectar lesiones persistentes o si la baciloscopia es positiva, incluso si los valores son menores que los iniciales. Se presenta el caso de una mujer de 48 ...
Células Espumosas/patología,
Células Gigantes de Cuerpo Extraño/patología,
Lepra Lepromatosa/patología,
Piel/patología,
Antígenos CD/análisis,
Antígenos de Diferenciación Mielomonocítica/análisis,
Biopsia,
Pared Celular/química,
Quimioterapia Combinada,
Células Espumosas/química,
Células Espumosas/microbiología,
Células Gigantes de Cuerpo Extraño/química,
Células Gigantes de Cuerpo Extraño/microbiología,
Interacciones Huésped-Patógeno,
Leprostáticos/uso terapéutico,
Lepra Lepromatosa/tratamiento farmacológico,
Lípidos/análisis,
Mycobacterium leprae/química,
Mycobacterium leprae/aislamiento & purificación,
Piel/microbiología,
Vacuolas
Abstract: The aim of this study was to evaluate macrophage M1 and M2 subpopulations in radicular cysts (RCs) and periapical granulomas (PGs) and relate them to clinical and morphological aspects. M1 macrophages were evaluated by the percentage of CD68 immunostaining associated with the inflammatory cytok...
Antígenos CD/análisis,
Antígenos de Diferenciación Mielomonocítica/análisis,
Enfermedad Crónica,
Inmunohistoquímica,
Macrófagos/patología,
Persona de Mediana Edad,
Granuloma Periapical/patología,
Quiste Radicular/patología,
Receptores de Superficie Celular/análisis,
Valores de Referencia,
Estadísticas no Paramétricas,
Factor de Necrosis Tumoral alfa/análisis
Vitoria, Webster Oliveira;
Thomé, Letícia Silva;
Kanashiro-Galo, Luciane;
Carvalho, Leda Viegas de;
Penny, Ricardo;
Santos, Washington Luis Conrado;
Vasconcelos, Pedro Fernando da Costa;
Sotto, Mirian Nacagami;
Duarte, Maria Irma Seixas;
Quaresma, Juarez Antonio Simões;
Pagliari, Carla.
Abstract INTRODUCTION: Dengue is an important mosquito-borne disease in tropical and subtropical regions. Adhesion molecules have not been systematically characterized in the renal tissue of patients with severe dengue (SD). The objective of this study was to detect viral antigens in samples from patie...
Antígenos CD/sangre,
Antígenos CD/fisiología,
Antígenos Virales/sangre,
Biomarcadores/sangre,
Cadherinas/sangre,
Cadherinas/fisiología,
Progresión de la Enfermedad,
Selectina E/sangre,
Selectina E/fisiología,
Endotelio/fisiopatología,
Inmunohistoquímica,
Molécula 1 de Adhesión Intercelular/sangre,
Molécula 1 de Adhesión Intercelular/fisiología,
Persona de Mediana Edad,
Dengue Grave/sangre,
Dengue Grave/fisiopatología,
Regulación hacia Arriba,
Molécula 1 de Adhesión Celular Vascular/sangre,
Molécula 1 de Adhesión Celular Vascular/fisiología
