Results: 6

Identificación del alelo HLA B*57: 01 en una población militar, de Lima-Perú

Rev. chil. infectol; 41 (2), 2024
El alelo HLA B*57:01 es un marcador genético asociado con la hipersensibilidad al fármaco anti-retroviral abacavir (ABC) y su frecuencia en la población peruana todavía es desconocida. El objetivo fue identificar el alelo HLA B*57:01 en una población militar de Lima, Perú. Se reclutaron 43 personas...

Variabilidad genética y epigenética, y la pandemia de Covid-19

Salud pública Méx; 62 (5), 2020

Optimization of HLA-B*27 ALLELE Genotyping by PCR-SSP

Clinics; 75 (), 2020
OBJECTIVES: HLA-B27 is strongly associated with ankylosing spondylitis (AS) and its presence helps to confirm AS diagnosis. Due to the high HLA polymorphism and the differentiated contribution of alleles and molecules encoded by them, HLA-B*27 allele identification is relevant in the clinical follow-up, ...

HLA alleles in renal transplant recipients with nonmelanoma skin cancer in southeastern Brazil

An. bras. dermatol; 94 (3), 2019
Abstract: Background: Renal transplant recipients are submitted to immunosuppression to avoid graft rejection, which makes them susceptible to various conditions. Furthermore, these individuals present malignant tumors more frequently than the general population, including nonmelanoma skin cancer. The i...

A systematic review on the influence of hla-b polymorphisms on hiv-1 mother-to-child-transmission

Braz. j. infect. dis; 23 (1), 2019
ABSTRACT Background: Mother-to-child-transmission (MTCT) is the main route of HIV-1 infection in children. Genetic studies suggest HLA-B alleles play an important role on HIV-1 transmission, progression, and control of HIV-1 infection. Objective: To evaluate which polymorphisms of HLA-B are involved in...

Lack of association between alopecia areata and HLA class I and II in a southeastern Brazilian population

An. bras. dermatol; 91 (3), 2016
Abstract: Background: Alopecia areata (AA) is a common disorder of unknown etiology that affects approximately 0.7% to 3.8% of patients among the general population. Currently, genetic and autoimmune factors are emphasized as etiopathogenic. Studies linking Human Leukocyte Antigens (HLA) to AA have sugg...