Results: 12

Extract of Ascaris suum induces TGF-β and early production of IgG1 in experimental autoimmune hepatitis

Abstract In experimental autoimmune hepatitis (EAH) of Th1 profile, an extract of adult Ascaris suum worms (ASC) was previously found to deviate the immune response to a Th2/IL-10 pattern. Here, the effects of treatment with ASC on production of TGF-β and the anti-Ascaris isotypes IgG1 and IgG2a in ...

Screening of Strongyloides infection using an ELISA test in transplant candidates

Clinics; 74 (), 2019
OBJECTIVES: Hyperinfection or disseminated strongyloidiasis has been frequently reported after transplants and is related to high mortality. This study aimed to screen for strongyloidiasis using serological diagnoses in transplant candidates. METHODS: An ELISA test was performed with filariform larvae o...

Evaluation of the recombinant antigens Wb14 and WbT for the capture antibody diagnosis of lymphatic filariasis

Mem. Inst. Oswaldo Cruz; 113 (5), 2018
BACKGROUND Lymphatic filariasis (LF) is a parasitic disease caused mainly by the Wuchereria bancrofti worm and that affects up to 120 million people worldwide. LF is the second cause of chronic global deformity, responsible for 15 million people with lymphedema (elephantiasis) and 25 million men with sc...

Análisis proteómico de los productos de excreción-secreción de cuatro aislados de Trichinella spiralis obtenidos de hospederos accidentales

Resumen: Introducción: Trichinella spiralis es un nemátodo tisular que se aloja en el músculo esquelético de humanos y otros mamíferos y causa una serie de alteraciones fisiológicas. Las proteínas de los productos de excreción-secreción de T. spiralis juegan un papel importante en la aparición...

Enzyme-linked immunosorbent assay for diagnosis of Amphimerus spp. liver fluke infection in Humans

Mem. Inst. Oswaldo Cruz; 112 (5), 2017
BACKGROUND Amphimerus spp. is a liver fluke that infects humans and domestic animals. It is highly prevalent in some Ecuadorian communities. Currently, diagnosis is based on the microscopic observation of eggs in faeces, but this has variable sensitivity. More sensitive methods are needed for diagnostic ...

Validez de tres métodos de inmuno-diagnóstico de neurocisticercosis: revisión sistemática de la literatura con meta-análisis 1960-2014

Rev. chil. infectol; 34 (1), 2017
Introduction: The screening of neurocysticercosis is complex and immunological methods have varying validity. Objective: To evaluate the validity of ELISA for antigen and antibody, and EITB for antibody in the screening of neurocysticercosis. Methods: Meta-analysis of diagnostic tests with an ex-ante pro...

Identification of IgE and IgG1 specific antigens in Echinococcus granulosus cyst fluid

Braz. j. med. biol. res; 50 (7), 2017
Cystic echinococcosis (CE) is an anthropozoonotic disease with worldwide distribution and is caused by the cestode Echinococcus granulosus. Anaphylactic shock induced by CE rupture is a serious complication especially in patients with hydatid infections, as the resulting leakage of fluid contains highly ...

Prospects for a nonliving vaccine against Schistosomiasis based on cell-mediated immune resistance mechanisms

Mem. Inst. Oswaldo Cruz; 82 (supl.4), 1987
We have designed a vaccine model based on induction of cell-mediated immunity and shown that it protects mice against Schistosoma mansoni infection. Mice are immunized by intradermal injection with schistosome antigens plus BCG. Resistance is dependent on the route of antigen presentation and the adjuvan...

Analysis of antibody responses of Schistosoma mansoni infected patients against schistosomal antigens

Mem. Inst. Oswaldo Cruz; 82 (supl.4), 1987