Results: 15

Tratamiento hormonal de la pedofilia: ¿puede curar la pedofilia con la castración química?

Históricamente la sociedad ha rechazado el abuso sexual de menores de 13 años, dictándose leyes al respecto. La justicia luego de un debido proceso condenaba al victimario con reclusión incluso hasta la década del 70-80, con orquiectomía. Los adelantos en neurobiología, endocrinología, sicofarmac...

Influence of statins in metastatic castration-resistant prostate cancer patients treated with new antiandrogen therapies: a systematic review and meta-analysis

ABSTRACT Objective To evaluate whether the addition of statins to the new antiandrogens (enzalutamide or abiraterone) affects overall survival in patients with metastatic castration-resistant prostate cancer. Methods We searched studies in English language including the keywords statins, overall surv...

Clinical and surgical assistance in prostate cancer during the COVID-19 Pandemic: implementation of assistance protocols

Int. braz. j. urol; 46 (supl.1), 2020
ABSTRACT Purpose: Propose an approach of prostate cancer (PCa) patients during COVID-19 pandemic. Material and Methods: We conducted a review of current literature related to surgical and clinical management of patients during COVID-19 crisis paying special attention to oncological ones and especially ...

Salud ósea en personas transgénero
Bone health in transgender subjects

Actual. osteol; 16 (3), 2020
Una persona transgénero es aquella en la cual el género autopercibido difiere del asignado al nacer, mientras que el término cisgénero es utilizado en aquellos individuos no trans. El tratamiento hormonal cruzado (THC) constituye una opción para lograr caracteres sexuales secundarios deseados. Es co...

Síndrome de Insensibilidad Completa a Andrógenos (SICA): reporte de un caso clínico

Rev. méd. Maule; 34 (2), 2019
INTRODUCTION: Complete Androgen Insensitivity Syndrome (CAIS) is a X-linked recessive disorder characterized by a complete resistance of the Androgen Receptor (AR) to androgens. As a result, affected individuals present complete female external genitalia, but are genetically male with a 46, XY karyotype....

Síndrome dos ovários policísticos: tratamento das manifestações androgênicas

Femina; 47 (9), 2019
A síndrome dos ovários policísticos (SOP) é um distúrbio endócrino-metabólico muito frequente no período reprodutivo. Quando associado ao distúrbio metabólico, as mulheres com SOP podem ter ainda risco acrescido para doença cardiovascular. O objetivo deste manuscrito é descrever as repercuss...

Enhancing PSMA-uptake with androgen deprivation therapy - a new way to detect prostate cancer metastases?

Int. braz. j. urol; 45 (3), 2019
ABSTRACT Purpose: 68Ga-PSMA PET/CT imaging is a promising modality for the staging of recurrent prostate cancer (PCa). Current evidence suggests limited diagnostic value of the 68Ga-PSMA PET/CT in PSA-levels ≤0.3ng/mL. Experimental data have demonstrated an increase in PSMA-expression in PCa metas...

Cost-effectiveness analysis of abiraterone, docetaxel or placebo plus androgen deprivation therapy for hormone-sensitive advanced prostate cancer

Einstein (Säo Paulo); 17 (2), 2019
ABSTRACT Objective To evaluate the cost-effectiveness of the addition of chemotherapy or abiraterone to androgen deprivation. Methods We developed an analytical model to determine the cost-effectiveness of the addition of docetaxel or abiraterone versus androgen deprivation therapy alone. Direct and ...

Informe de evaluación científica basada en la evidencia disponible: cáncer de próstata
Scientific evaluation report based on available evidence: prostate cancer

INTRODUCCIÓN: El cáncer de próstata es uno de los tumores sólidos más frecuentes en hombres en el mundo, siendo el más incidente en Europa con una tasa de 214 casos por cada 1000 hombres, superando al cáncer de pulmón y colorrectal. En Chile, el cáncer de próstata se ubica como la segunda causa...