ABSTRACT Objective To evaluate the performance of enzyme-linked immunosorbent assay and indirect immunofluorescence methods for the detection of antineutrophil cytoplasmic antibodies in a routine clinical laboratory setting. Methods A total of 227 samples were tested by indirect immunofluorescence an...
ABSTRACT Pauci-immune glomerulonephritis (GN) is more common in elderly people compared to children and the etiology is not completely understood yet. Antineutrophil cytoplasmic antibody (ANCA) positivity occurs in 80% of the patients. We report a case of a 7-year-old girl who presented with malaise and ...
Antiinflamatorios/administración & dosificación,
Antiinflamatorios/uso terapéutico,
Anticuerpos Anticitoplasma de Neutrófilos/sangre,
Biopsia,
Creatinina/sangre,
Ciclofosfamida/administración & dosificación,
Ciclofosfamida/uso terapéutico,
Estudios de Seguimiento,
Glomerulonefritis/sangre,
Glomerulonefritis/diagnóstico,
Glomerulonefritis/tratamiento farmacológico,
Inmunosupresores/administración & dosificación,
Inmunosupresores/uso terapéutico,
Riñón/patología,
Metilprednisolona/administración & dosificación,
Metilprednisolona/uso terapéutico,
Prednisona/administración & dosificación,
Prednisona/uso terapéutico,
Resultado del Tratamiento
ABSTRACT Background and objectives: Anti-neutrophil cytoplasmic autoantibodies (ANCA) associated vasculitis is a small vessel vasculitis with insufficient epidemiologic estimates in the United States. We aimed to determine demographic and clinical features of ANCA associated vasculitis patients presenti...
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/sangre,
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/epidemiología,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/sangre,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/epidemiología,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/mortalidad,
Anticuerpos Anticitoplasma de Neutrófilos/sangre,
Biopsia,
Comorbilidad,
Creatinina/sangre,
Estudios de Seguimiento,
Incidencia,
Estimación de Kaplan-Meier,
Riñón/patología,
Fallo Renal Crónico/sangre,
Fallo Renal Crónico/epidemiología,
Mortalidad/tendencias,
New York/epidemiología,
Diálisis Renal,
Estudios Retrospectivos,
Atención Terciaria de Salud
Abstract INTRODUCTION: Based on reports, infection with Mycobacterium tuberculosis is believed to induce the development of antibodies that are considered to be biological indicators for the diagnosis of some other diseases. However, conflicting results have been published regarding the presence of ant...
Aguirre, Verónica;
Alvo, Miriam;
Ardiles, Leopoldo;
Fierro, Alberto;
Goecke, Annelise;
Iruretagoyena, Mirentxu;
Jalil, Roberto;
Massardo, Loreto;
Méndez, Gonzalo P;
Palma, Sergio;
Roessler, Emilio;
Silva, Francisco;
Wurgaft, Andrés.
Renal involvement is a frequent complication in antineutrophil cytoplasmic antibodies (ANCA)associated vasculitides, adding morbidity and mortality, such as chronic kidney disease and the need for renal replacement therapy. With the aim of reaching a consensus on relevant issues regarding the diagnosis, ...
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/complicaciones,
Anticuerpos Anticitoplasma de Neutrófilos/sangre,
Enfermedades Renales/etiología,
Enfermedades Renales/terapia,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/sangre,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/diagnóstico,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/terapia,
Chile,
Quimioterapia de Mantención,
Inducción de Remisión,
Sociedades Médicas
Abstract The pauci-immune crescentic glomerulonephritis (PICGN) is generally associated with small-vessel vasculitis with a few reported cases associated with other autoimmune diseases such as Systemic Lupus Erythematosus (SLE). We present the case of a female 34-year-old patient with acute kidney injury...
Abstract: Background: The clinical significance of anti-neutrophil cytoplasmic antibodies in patients with new-onset systemic lupus erythematosus, especially in systemic disease accompanied by interstitial lung disease remains to be elucidated. Objectives: This study was designed to investigate the rol...
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/inmunología,
Anticuerpos Anticitoplasma de Neutrófilos/sangre,
Enfermedades Pulmonares Intersticiales/inmunología,
Lupus Eritematoso Sistémico/inmunología,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/complicaciones,
Estudios Transversales,
Ensayo de Inmunoadsorción Enzimática,
Técnica del Anticuerpo Fluorescente Indirecta,
Enfermedades Pulmonares Intersticiales/etiología,
Lupus Eritematoso Sistémico/diagnóstico por imagen,
Neutrófilos/enzimología,
Pronóstico,
Tomografía Computarizada por Rayos X/métodos
SUMMARY Introduction: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disease that can affect multiple organs, the kidney being one of the most affected. Apart from the diagnostics value of ANCA, they have also been advocated as biomarkers of the disease activity. Rece...
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/sangre,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/complicaciones,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/patología,
Anticuerpos Anticitoplasma de Neutrófilos/sangre,
Biomarcadores,
Biopsia,
Proteína C-Reactiva/análisis,
Ensayo de Inmunoadsorción Enzimática,
Riñón/patología,
Enfermedades Renales/etiología,
Enfermedades Renales/patología,
Persona de Mediana Edad,
Mieloblastina/sangre,
Peroxidasa/sangre,
Pronóstico,
Proteinuria,
Recurrencia,
Valores de Referencia,
Estudios Retrospectivos,
Estadísticas no Paramétricas
CONTEXT: The term pulmonary-renal syndrome has been used frequently to describe the clinical manifestations of a great number of diseases in which pulmonary hemorrhage and glomerulonephritis coexist. The classic example of this type of vasculitis is Goodpasture´s syndrome, a term used to describe the as...
