Yu, Zhangjie;
Peng, Fang;
Liu, Hanxuan;
Qiu, Yinyin;
Ye, Chunji;
Peng, Jiahao;
Xu, Buyun;
Qi, Ying;
Zhou, Yan;
Tang, Weiliang.
This study investigates the efficacy and mechanisms of Kuanxiong Aerosol (KXA) on coronary microvascular dysfunction (CMD) in rats. Thirty-two Sprague-Dawley rats were divided into control, model, KXA, and nicorandil groups, receiving respective treatments for three weeks. The CMD...
Corrêa, Allan J. C;
Andrade, Bruno de A;
Neri, Patrícia M. da S;
Castro, Valerium T. N. de A. e;
Araújo, Rosilma O;
de Sena, Kêsia X. da F. R;
Machado, Kivia dos S;
Araújo, Thiago A. de S;
Sobrinho, Tadeu J. da S. P;
de Amorim, Elba L. C.
In this work, we evaluate the antimicrobial properties of three groups of plants selected by the ethnopharmacological method, reported ashaving antimicrobial and/or anti-inflammatory properties by a rural community in the Brazilian State of Pernambuco. The samples were divided into groups o...
Bisphenol A (BPA) have been reported to induced reprotoxicity in rats. This study was conducted to find out the ameliorative properties of aqueous extract of Cyperus esculentus (tigernut) on BPA induced testicular toxicity in Wistar rats.Methods: Twenty male rats were divided randomly into 4 groups (n=5)...
Enfermedades Testiculares/prevención & control,
Testículo/efectos de los fármacos,
Cyperus/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/aislamiento & purificación,
Enfermedades Testiculares/inducido químicamente,
Enfermedades Testiculares/metabolismo,
Enfermedades Testiculares/patología,
Testículo/metabolismo,
Antiinflamatorios/aislamiento & purificación,
Antiinflamatorios/farmacología,
Antioxidantes/aislamiento & purificación,
Antioxidantes/farmacología,
Modelos Animales de Enfermedad,
Bisfenol A Glicidil Metacrilato/efectos adversos,
Ratas Wistar,
Espermatozoides/efectos de los fármacos,
Espermatozoides/metabolismo,
Espermatozoides/patología
Objetivo:Identificar propriedades químicas e farmacológicas do gênero Copaifera no tratamento de lesões e feridas. Método: Revisão integrativa da literatura realizada nas bases de dados LILACS, MEDLINE, PubMed, Taylor & Francis e Scopus, em janeiro de 2022, por meio da estratégia de busca: �...
Triterpenes are very important secondary metabolites with wide structural diversity and
significant role in pharmacy and medicine.
In the present research, a comparative study of
pharamacological activities of the triterpene fractions obtained from several pla...
Silva, Márcia J. A;
Boleti, Ana Paula A;
Acho, Leonard D. R;
Campos, Jaqueline F;
Neto, José P. M;
Guimaraes, Anderson;
Silva, Felipe M. A;
Koolen, Hector H. F;
Santos, Edson L;
Lima, Emerson S.
Bertholletia excelsa is native to the Amazon Rainforest and is popularly known as the Brazil nut. It has socioeconomic importance due its nuts being a great export product. There are few studies in the literature regarding the biotechnological potential of its bark, although it is used in folk medicin...
Bertholletia/química,
Plantas Medicinales,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Antiinflamatorios/farmacología,
Antioxidantes/farmacología,
Brasil,
Antiinflamatorios/química,
Antioxidantes/química,
Macrófagos,
Peritonitis/tratamiento farmacológico,
Citoprotección,
Óxido Nítrico,
Corteza de la Planta/química,
Estrés Oxidativo,
Cromatografía Líquida con Espectrometría de Masas
Urtica circularis is an Argentinean species traditionally used to treat inflammation symptoms and oxidative stress-related diseases. Considering the uses in folk medicine, the purpose of this work was to evaluate and compare the anti-inflammatory and antioxidant activities of two different U. ...
Abstract Acai (Euterpe oleracea Mart.) and guarana (Paullinia cupana Kunth) are native species from the Amazon Forest that in folk medicine are used to treat several diseases due to their anti-inflammatory and antioxidant properties. This review brings together findings from different studies on the pote...
Copaifera spp. essential oil (EOC) was extracted by hydrodistillation of Copaifera oleoresin (COR). The EOC was characterized by GC/MS and a novel EOC-loaded nanoemulsion was developed to enhance the EOC solubility and to evaluate its utility as antinflammatory. EOC contain 14 volatile compounds (includ...
Fabaceae/química,
Aceites Volátiles/farmacología,
Aceites Volátiles/química,
Antiinflamatorios/farmacología,
Emulsiones/farmacología,
Nanopartículas,
Cromatografía de Gases y Espectrometría de Masas,
Sesquiterpenos Policíclicos/análisis,
Tensoactivos,
Temperatura,
Concentración de Iones de Hidrógeno,
Reología,
Pruebas de Toxicidad Aguda
SUMMARY: Skeletal muscle injury is an acute inflammatory condition caused by an inflammatory response. To reduce inflammatory cell infiltration and relieve skeletal muscle injury, efficient treatment is urgently needed. Nitric oxide is a free radical molecule reported to have anti-inflammatory effects. I...
Óxido Nítrico/farmacología,
Antiinflamatorios/farmacología,
Enfermedades Musculares/inducido químicamente,
Venenos Elapídicos/toxicidad,
Mioblastos/efectos de los fármacos,
Supervivencia Celular,
Ratas Sprague-Dawley,
Modelos Animales de Enfermedad,
Inmunohistoquímica,
Ensayo de Inmunoadsorción Enzimática,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Inflamación,
NG-Nitroarginina Metil Éster,
Caspasas,
Técnicas In Vitro
