Silva , Clemente;
Boene, Simone;
Datta , Debayan;
Valbona, Eduard Rovira;
Díaz, Andrés Aranda 3 4;
Cisteró, Pau;
Hathaway , Nicholas;
Tessema, Sofonias;
Chidimatembue, Arlindo;
Matambisso, Glória;
Nhama, Abel;
Macete, Eusebio;
Pujol, Arnau;
Nhamussua , Lidia;
Galatas, Beatriz;
Guinovart, Caterina;
Enosse, Sónia;
Carvalho, Eva;
Rogier, Eric;
Plucinski, ateusz M;
Colborn, James;
Zulliger, Rose;
Saifodine, Abuchahama;
Alonso, Pedro L;
Candrinho , Baltazar;
Greenhouse , Bryan 3;
Saute, Francisco;
Mayor, Alfredo.
Mozambique is one of the four African countries which account for over half of all malaria deaths worldwide, yet little is known about the parasite genetic structure in that country. We performed P. falciparum amplicon and whole genome sequencing on 2251 malaria-infected blood samples collected in 2015 a...
Las infecciones por malaria incrementan el riesgo de presentar complicaciones en el binomio madre-feto. En Venezuela, la casuística de este grupo vulnerable no se ha actualizado en los últimos años. El objetivo de esta revisión narrativa fue describir exhaustivamente qué es la malaria asociada al em...
Abstract Plasmodium falciparum resistance to Chloroquine (CQ) is a significant cause of mortality and morbidity worldwide. There is a paucity of documented data on the prevalence of CQ-resistant mutant haplotypes of Pfcrt and Pfmdr1 genes from malaria-endemic war effected Federally Administered Tribal Ar...
Abstract We critically analyzed clinical trials performed with chloroquine (CQ) and hydroxychloroquine (HCQ) with or without macrolides during the first wave of COVID-19 and discussed the design and limitations of peer-reviewed studies from January to July 2020. Seventeen studies were eligible for the di...
Abstract Genetic variability in the host metabolism of antimalarial drugs influenced by the polymorphisms of cytochrome P450 (CYP) could lead to significant changes in antimalarial treatment response. However, little is known about the frequency of alleles CYP2B6, CYP2C8, and CYP2D6 in an Amazonian popul...
Introducción. La tafenoquina fue aprobada en el 2018 por la Food and Drug Administration de Estados Unidos y, en el 2019, por la Therapeutic Goods Administration en Australia. Su administración en dosis única y su mecanismo de acción en las fases aguda y latente han sido objeto de estudio para cambia...
Introducción: La malaria es una de las enfermedades infecciosas más importantes y para tratarla además de medicamentos, la población emplea plantas medicinales. El objetivo fue establecer los factores asociados a malaria y las plantas empleadas para su tratamiento en habitantes de Corozal. Método: S...
Objetivo. Determinar el estado actual de la prevalencia de Plasmodium en pacientes febriles que acuden al Hospital Básico Franklin Tello Nuevo Rocafuerte, cantón Aguarico, comparando con los datos de otros estudios epidemiológicos de la misma zona y la frontera con el vecino país de Per...
Solanum nudum Dunal (Solanaceae) is most commonly known andused by the population of the colombian Pacific coast as an antimalarial treatment. This article study into optimization and quantitative analysis of compounds steroidal over time of development of this species when grown in vitro and wild. A n...
Abstract Morinda lucida leaves are largely used by Congolese traditional healers for the treatment of uncomplicated malaria. The antimalarial activity of their ethanolic extract has been confirmed both in vitro and in vivo. However, the development of relevant formulations for potential clinical applicat...
