LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Identification of cancer inhibitors from Hystrix brachyura bezoar extracts using LC - MS multivariate data analysis and in silico evaluation on Bcl - 2, cyclin B/CDK1, VEGF and NM23 - H1

Khan, Al’ aina Yuhainis Firus; Ahmed, Qamar Uddin; Khatib, Alfi; Ibrahim, Zalikha; Nipun, Tanzina Sharmin; Natto, Hatim Abdullah; Saiman, Mohd Zuwairi; Zakaria, Zainul Amiruddin; Wahab, Ridhwan Abdul.

Bol. latinoam. Caribe plantas med. aromát; 23 (1), 2024

Hystrix brach yura bezoar is calcified undigested material found in the gastrointestinal tract known for various medicinal benefits including as an anticancer agent. However, the H. brachyura population has been declining due to its demand and is under Malaysian law p...

Bezoares/metabolismo, Análisis Multivariante, Braquiuros/química, Antineoplásicos Fitogénicos/química, Cromatografía Líquida con Espectrometría de Masas, Simulación del Acoplamiento Molecular, Metabolómica, Fitoquímicos

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Cytotoxic effect of hydroalcoholic extract of Cota tinctoria (L) J. Gay on AGS and Hep-G2 cancer cell lines

Shamloo, Sharareh; Marandi, Sayeh Jafari; Tajadod, Golnaz; Majd, Ahmad; Rahimi, Roja.

Bol. latinoam. Caribe plantas med. aromát; 21 (1), 2022

Cota tinctoria is a medicinal plant which has been used for management of cancer in folk medicine of various regions. The aim of present study is to investigate cytotoxic activity of different concentrations of hydroalcoholic extract of C. tinctoria flowers on gastric (AGS) and liver (Hep-G2) cancer ce...

Asteraceae/química, Extractos Vegetales/administración & dosificación, Neoplasias Hepáticas/tratamiento farmacológico, Extractos Vegetales/farmacología, Línea Celular Tumoral/efectos de los fármacos, Anthemis/química, Células Hep G2/efectos de los fármacos, Neoplasias Gástricas/tratamiento farmacológico, Antineoplásicos Fitogénicos/administración & dosificación, Antineoplásicos Fitogénicos/farmacología, Extractos Vegetales/química, Antineoplásicos Fitogénicos/química, Técnicas de Cultivo de Célula, Compuestos Fenólicos/análisis, Flavonoides/análisis

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Antitumor activity of chemical modified natural compounds

Oliveira, Marilda Meirelles de.

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991

Search of new activity substances starting from chemotherapeutic agents, continously appears in international literature. Perhaps this search has been done more frequently in the field of anti-tumor chemotherapy on account of the unsuccess in saving advanced stage patients. The new point in this matter d...

Antineoplásicos, Antineoplásicos Fitogénicos/síntesis química, Antineoplásicos Fitogénicos/química, Antineoplásicos Fitogénicos/aislamiento & purificación, Brasil, Diseño de Fármacos, Evaluación de Medicamentos, Ensayos de Selección de Medicamentos Antitumorales

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