A simple and sensitive high-performance liquid chromatographic method to measure antipyrine and its metabolites in human urine
Rev. farm. bioquim. Univ. Säo Paulo; 32 (2), 1996
A method which permits the simultaneous HPLC analysis of antipyrine (A), 3-hydroxymethylantipyrine (HMA), 4-hydroxyantipyrine (HOA) and norantiopyrine (NORA) using a single extraction step in a five minute chromatographic run is described. Only 500 micraLitro of urine were necessary for the quantitation ...