Comparison of cardiotoxicity between N-methyl-glucamine and miltefosine in the treatment of American cutaneous leishmaniasis
An. bras. dermatol; 96 (4), 2021
Results: 9
Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
Rev. Soc. Bras. Med. Trop; 54 (), 2021
Abstract Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with milt...
American tegumentary leishmaniasis: severe side effects of pentavalent antimonial in a patient with chronic renal failure
An. bras. dermatol; 94 (3), 2019
Abstract: Pentavalent antimonials are the first-line drug treatment for American tegumentary leishmaniasis. We report on a patient with chronic renal failure on hemodialysis who presented with cutaneous lesions of leishmaniasis for four months. The patient was treated with intravenous meglumine under str...
Anfotericina B/uso terapéutico, Antiprotozoarios/efectos adversos, Antiprotozoarios/uso terapéutico, Brasil, Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos, Leishmaniasis Cutánea/complicaciones, Leishmaniasis Cutánea/tratamiento farmacológico, Leishmaniasis Cutánea/patología, Antimoniato de Meglumina/efectos adversos, Diálisis Renal, Insuficiencia Renal Crónica/complicaciones
Treatment of cutaneous leishmaniasis with thermotherapy in Brazil: an efficacy and safety study
An. bras. dermatol; 93 (3), 2018
Abstract: BACKGROUND: Pentavalent antimonials remain as the standard drugs in the treatment of cutaneous leishmaniosis. The high cost, difficult administration, long treatment time, toxicity and increasing morbidity are factors that limit the use of these drugs. OBJECTIVES: To describe the response to ...
Antiprotozoarios/efectos adversos, Antiprotozoarios/uso terapéutico, Brasil, Intervalos de Confianza, Estudios Controlados Antes y Después, Resistencia a Medicamentos, Hipertermia Inducida/efectos adversos, Hipertermia Inducida/métodos, Hipertermia Inducida/normas, Leishmaniasis Cutánea/tratamiento farmacológico, Leishmaniasis Cutánea/patología, Leishmaniasis Cutánea/terapia, Ondas de Radio, Resultado del Tratamiento
Toxicidad, genotoxicidad y actividad anti-Leishmania de aceites esenciales obtenidos de cuatro (4) quimiotipos del género Lippia
Bol. latinoam. Caribe plantas med. aromát; 17 (1), 2018
Los aceites esenciales (AEs), pertenecientes al género Lippia, son candidatos interesantes de formulaciones tópicas en el tratamiento de la leishmaniasis cutánea (LC). El objetivo de este trabajo fue determinar el perfil toxicológico y la actividad anti-Leishmania de AEs obtenidos de plantas colo...
Lippia/química, Leishmaniasis Cutánea/tratamiento farmacológico, Ratones Endogámicos BALB C, Aceites Volátiles/farmacología, Colombia, Aceites Volátiles/efectos adversos, Ensayo Cometa, Genotoxicidad, Leishmania/efectos de los fármacos, Dermatitis por Contacto/etiología, Antiprotozoarios/farmacología, Antiprotozoarios/efectos adversos
Meglumine antimoniate intralesional infiltration for localised cutaneous leishmaniasis: a single arm, open label, phase II clinical trial
Mem. Inst. Oswaldo Cruz; 113 (9), 2018
BACKGROUND Cutaneous leishmaniasis (CL) is a world-wide health problem which currently lacks effective, affordable and easy to use therapy. Recently, the meglumine antimoniate (MA) intralesional infiltration was included among the acceptable therapies for New World leishmaniasis. While this approach is ...
Aspectos patológicos da intoxicação por aceturato de diminazeno em camelídeos sul-americanos
Pesqui. vet. bras; 37 (12), 2017
Aceturato de diminazeno é um fármaco quimioterápico sintético comumente usado na medicina veterinária para o tratamento de doenças causadas por parasitos hematozoários. Entretanto, seu uso pode levar a efeitos colaterais, como alterações neurológicas graves e morte. A criação de camelídeos ...
Efficacy and safety of amphotericin B deoxycholate versus N-methylglucamine antimoniate in pediatric visceral leishmaniasis: an open-label, randomized, and controlled pilot trial in Brazil
Rev. Soc. Bras. Med. Trop; 50 (1), 2017
ABSTRACT INTRODUCTION Despite their high toxicity, antimonials and amphotericin B deoxycholate are commonly used for treating visceral leishmaniasis (VL). Few studies showing conflictive data about their efficacy and adverse events in pediatric population are available. This study aimed to evaluate eff...
Anfotericina B/efectos adversos, Anfotericina B/uso terapéutico, Antiprotozoarios/efectos adversos, Antiprotozoarios/uso terapéutico, Ácido Desoxicólico/efectos adversos, Ácido Desoxicólico/uso terapéutico, Combinación de Medicamentos, Leishmaniasis Visceral/tratamiento farmacológico, Meglumina/efectos adversos, Meglumina/uso terapéutico, Antimoniato de Meglumina, Compuestos Organometálicos/efectos adversos, Compuestos Organometálicos/uso terapéutico, Proyectos Piloto, Resultado del Tratamiento
DRESS syndrome in ophthalmic patients
Arq. bras. oftalmol; 79 (3), 2016
ABSTRACT Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially fatal adverse drug reaction associated with skin rash, fever, eosinophilia, and multiple organ injury. A number of pharmacological agents are known to cause DRESS syndrome such as allopurinol, antico...
Antibacterianos/efectos adversos, Antiprotozoarios/efectos adversos, Biopsia, Síndrome de Hipersensibilidad a Medicamentos/etiología, Síndrome de Hipersensibilidad a Medicamentos/patología, Endoftalmitis/tratamiento farmacológico, Fiebre/patología, Inyecciones Intravítreas/efectos adversos, Piel/patología, Toxoplasmosis Ocular/tratamiento farmacológico