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Enhancing the aqueous solubility and dissolution of olanzapine using freeze-drying

Braz. j. pharm. sci; 47 (4), 2011
The aim of the present study was to develop an olanzapine freeze-dried tablet (FDT). The solubility and dissolution rate of poorly water-soluble olanzapine was improved by preparing a freeze-dried tablet of olanzapine using the freeze-drying technique . The FDT was prepared by dispersing the drug in an a...