LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties

Oliveira, Cláudia S; Caldeira, Cleópatra A. S; Diniz-Sousa, Rafaela; Romero, Dolores L; Marcussi, Silvana; Moura, Laura A; Fuly, André L; Carvalho, Cicília de; Cavalcante, Walter L. G; Gallacci, Márcia; Pai, Maeli Dal; Zuliani, Juliana P; Calderon, Leonardo A; Soares, Andreimar M.

J. venom. anim. toxins incl. trop. dis; 24 (), 2018

Cnidarians produce toxins, which are composed of different polypeptides that induce pharmacological effects of biotechnological interest, such as antitumor, antiophidic and anti-clotting activities. This study aimed to evaluate toxicological activities and potential as antitumor and antiophidic agents co...

Venenos de Cnidarios/farmacología, Antivenenos/toxicidad, Venenos de Crotálidos/inmunología, Bothrops, Neoplasias/inmunología

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Antivenomic approach of different Crotalus durissus collilineatus venoms

Oliveira, Isadora Sousa de; Pucca, Manuela Berto; Sampaio, Suely Vilela; Arantes, Eliane Candiani.

J. venom. anim. toxins incl. trop. dis; 24 (), 2018

Our group has previously performed a proteomic study verifying that individual variations can occur among Crotalus durissus collilineatus venoms. These variations may lead to differences in venom toxicity and may result in lack of neutralization of some components by antivenom. In this way, this study ai...

Venenos de Crotálidos, Antivenenos/toxicidad, Crotalus, Ensayo de Inmunoadsorción Enzimática

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Dano da radiaçäo gama em crotamina (Toxina da cascavel brasileira)

Costa, Tânia Alves da; Rogero, José Roberto.

Radiaçöes ionizantes afetam a estrutura das moléculas devido à destruiçäo das suas ligaçöes químicas. Estas alteraçöes químicas poderäo levar a uma mudança nas propriedades biológicas das mesmas, como tem sido demosntrado na literatura. A Crotamina foi obtida a partir de um "pool" do venen...

Cromatina/efectos de la radiación, Antivenenos/toxicidad, Venenos de Serpiente, Cromatografía, Brasil