LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Pharmacological evaluation of Rhazya stricta root extract

Mahmood, Rashid; Malik, Farnaz; Shamas, Shazia; Ahmed, Tanveer; Kausar, Mehran; Rubnawaz, Samina; Ashfaq, Muhammad; Hussain, Shahzad; Green, Brian Desmond; Mirza, Bushra.

Bol. latinoam. Caribe plantas med. aromát; 19 (2), 2020

The present study aimed to screen the Rhazya stricta Decne root for its antihyperglycemic and antioxidants potential through invitro assays along with phytochemical and elemental analyses. The crude extract was prepared through maceration and fractionated using solvent-solvent extraction technique. The s...

Apocynaceae/química, Raíces de Plantas/química, Hipoglucemiantes/farmacología, Antioxidantes/farmacología, Técnicas In Vitro, Extractos Vegetales/farmacología, Extractos Vegetales/química, Hipoglucemiantes/química, Antioxidantes/química, Dipeptidil-Peptidasas y Tripeptidil-Peptidasas/antagonistas & inhibidores, Glucemia/efectos de los fármacos, Fenoles/análisis, Flavonoides/análisis, Espectroscopía Infrarroja por Transformada de Fourier, Espectrofotometría Ultravioleta, Fitoquímicos

Fulltext

Antinociceptive and anti-inflammatory activities of a triterpene-rich fraction from Himatanthus drasticus

de-Almeida, S C X; da-Silva, Â C F; Sousa, N R T; Amorim, I H F; Leite, B G; Neves, K R T; Costa, J G M; Felipe, C F B; de-Barros Viana, G S.

Braz. j. med. biol. res; 52 (5), 2019

Himatanthus drasticus (Mart.) Plumel belongs to the Apocynaceae family and the latex from its trunk bark (Hd) is known as "janaguba milk". This latex is widely used in Northeast Brazil, mainly in the Cariri region, for its gastroprotective, anti-inflammatory, and antitumor properties. The objective of th...

Analgésicos/uso terapéutico, Antiinflamatorios/uso terapéutico, Apocynaceae/química, Biomarcadores/sangre, Modelos Animales de Enfermedad, Edema/tratamiento farmacológico, Inmunohistoquímica, Inflamación/tratamiento farmacológico, Ratas Wistar, Triterpenos/aislamiento & purificación, Triterpenos/uso terapéutico

Fulltext

In vivo and in vitro anti-inflammatory activity of Cryptostegia grandiflora Roxb. ex R. Br. leaves

Castro, Jenny P; Ocampo, Yanet C; Franco, Luis A.

Biol. Res; 47 (), 2014

BACKGROUND: Despite Cryptostegia grandiflora Roxb. ex R. Br. (Apocynaceae) leaves are widely used in folk Caribbean Colombian medicine for their anti-inflammatory effects, there are no studies that support this traditional use. Therefore, this work aimed to evaluate the effect of the total extract and pr...

Antiinflamatorios/farmacología, Apocynaceae/química, Edema/tratamiento farmacológico, Macrófagos/efectos de los fármacos, Extractos Vegetales/uso terapéutico, Línea Celular Tumoral/efectos de los fármacos, Citotoxinas/farmacología, Dinoprostona/análisis, Inflamación/tratamiento farmacológico, Óxido Nítrico/análisis, Oxitócicos/análisis, Peroxidasa/antagonistas & inhibidores, Hojas de la Planta/química, Ratones Endogámicos ICR

Fulltext