Results: 8

Protective Effects and Mechanisms of Huangqi Decoction Against Radiation-Induced Bystander Effects

Int. j. morphol; 41 (5), 2023
SUMMARY: The 12C6+ heavy ion beam irradiation can cause bystander effects. The inflammatory cytokines, endocrine hormones and apoptotic proteins may be involved in 12C6+ irradiation-induced bystander effects. This study characterized the protective effects and mechanisms of Huangqi decoction (HQD) agains...

Radiotherapy and immune response: the systemic effects of a local treatment

Clinics; 73 (supl.1), 2018
Technological developments have allowed improvements in radiotherapy delivery, with higher precision and better sparing of normal tissue. For many years, it has been well known that ionizing radiation has not only local action but also systemic effects by triggering many molecular signaling pathways. The...

Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes

Braz. j. med. biol. res; 51 (8), 2018
Excessive exposure to ultraviolet (UV) rays can cause damage of the skin and may induce cancer, immunosuppression, photoaging, and inflammation. The long non-coding RNA (lncRNA) HOX antisense intergenic RNA (HOTAIR) is involved in multiple human biological processes. However, its role in UVB-induced kera...

Effects of exposure to 2100 MHz GSM-like radiofrequency electromagnetic field on auditory system of rats

Abstract Introduction: The use of mobile phones has become widespread in recent years. Although beneficial from the communication viewpoint, the electromagnetic fields generated by mobile phones may cause unwanted biological changes in the human body. Objective: In this study, we aimed to evaluate the ...

Low-level laser irradiation promotes proliferation of cryopreserved adipose-derived stem cells

Einstein (Säo Paulo); 15 (3), 2017
ABSTRACT Objective To evaluate the effect of low-level laser irradiation on proliferation and viability of murine adipose-derived stem cells previously submitted to cryopreservation. Methods Adipose-derived stem cells were isolated from inguinal fat pads of three mice, submitted to cryopreservation i...

Active caspase-3 expression levels as bioindicator of individual radiosensitivity

An. acad. bras. ciênc; 89 (1,supl), 2017
ABSTRACT Several molecules and events involved in cell response to radiation-induced damage have been investigated towards a personalized radiotherapy. Considering the importance of active caspase-3 in the proteolytic cascade that ensures radiation-induced apoptosis execution, this research was designed ...

The effects of riboflavin and ultraviolet light on keratocytes cultured in vitro

Arq. bras. oftalmol; 79 (3), 2016
ABSTRACT Purpose: To culture quiescent human keratocytes and evaluate the effects of ultraviolet light and riboflavin on human corneal keratocytes in vitro. Methods: Keratocytes were obtained from remaining corneoscleral ring donor corneas previously used in corneal transplant surgeries and cultured in...

The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats

Acta cir. bras; 31 (2), 2016
PURPOSE: To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats. METHODS: Pregnant rats in the experimental group were exposed to radiation for six, 12, and 24 hours daily for 20 days. No radiation was given to the pregnan...