LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Gastroprotective potential and mechanisms of action of Hedera nepalensis

Shahzad, Naeem; Anjum, Irfan; Ahsan, Haseeb; Alamgeer, ; Syed, Shahzad Khurrum; Mushtaq, Muhammad Naveed.

Braz. J. Pharm. Sci. (Online); 59 (), 2023

Abstract Hedera nepalensis (H. nepalensis) , belonging to the family Araliaceae, is a medicinal plant traditionally used to treat stomach problems. The current study investigated the gastroprotective potential and the mechanism of action of H. nepalensis in diclofenac-and ethanol-induced ulcer models. An...

Araliaceae/clasificación, Plantas Medicinales, Antioxidantes, Diclofenaco/agonistas, Úlcera/inducido químicamente, Úlcera Gástrica/patología, ddcs0515740, Cromatografía Líquida de Alta Presión/métodos, Espectroscopía Infrarroja por Transformada de Fourier/métodos, Estómago/anomalías, Hedera/clasificación

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Process optimization of physicochemical properties of spray-dried Hydrocotyle umbellata L. extract

Oliveira, Matheus Gabriel de; Moreira, Guilherme Gomes; Paz, Andressa Tuane Santana; Oliveira, Thiago Levi Silva; Silva, Luís Antônio Dantas; Conceição, Edemilson Cardoso da; Borges, Leonardo Luiz; Silva, Vinicius Barreto da; Paula, José Realino de.

Braz. J. Pharm. Sci. (Online); 59 (), 2023

Abstract Hydrocotyle umbellata L., Araliaceae, is a species that is recommended in Ayurvedic medicine for its effects on the central nervous system, such as anxiolytic and memory-stimulant effects. Despite the medicinal potential of this species, its phytopharmaceutical and technological potential to pro...

Araliaceae/clasificación, Optimización de Procesos, Plantas Medicinales/efectos adversos, Fitoterapia/instrumentación, Medicina Ayurvédica, Secado por Pulverización

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Ethnopharmacological activity of Hedera nepalensis K. Koch extracts and lupeol against alloxan-induced type I diabetes

Hashmi, Waleed Javed; Ismail, Hammad; Jafri, Laila; Mirza, Bushra.

Braz. J. Pharm. Sci. (Online); 56 (), 2020

In this study, we investigated the protective effects of Hedera nepalensis crude extract, its fractions and lupeol in alloxan-induced diabetic rats. Lupeol and n-hexane (HNN) fraction significantly reduced the blood glucose level by increasing insulin level in time dependent manner, and also significantl...

Araliaceae/clasificación, Plantas Medicinales/metabolismo, Diabetes Mellitus Tipo 1/inducido químicamente, Aloxano/efectos adversos, Mezclas Complejas/efectos adversos, Insulina, Hedera/efectos adversos

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