Properties of realgar bioleaching using an extremely acidophilic bacterium and its antitumor mechanism as an anticancer agent
Biol. Res; 50 (), 2017
Realgar is a naturally occurring arsenic sulfide (or Xionghuang, in Chinese). It contains over 90% tetra-arsenic tetrasulfide (As4S4). Currently, realgar has been confirmed the antitumor activities, both in vitro and in vivo, of realgar extracted using Acidithiobacillus ferrooxidans (A. ferrooxidans). Bi...
Acidithiobacillus thiooxidans/metabolismo, Antineoplásicos/farmacología, Arsenicales/farmacología, Sulfuros/farmacología, Antineoplásicos/química, Apoptosis/efectos de los fármacos, Arsenicales/química, Arsenicales/metabolismo, Proliferación Celular/efectos de los fármacos, Sulfuros/química, Sulfuros/metabolismo, Línea Celular Tumoral, Sinergismo Farmacológico, Células K562, Fenómenos Toxicológicos