LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Suppression of nitrosative stress and inflammation of the knee joint synovium in collagen type ii-induced rheumatoid arthritis by the inhibition of glycogen synthase kinase-3ß

Mirdad, Tarek M; Al-Ani, Bahjat; Aseeri, Fareed F; Kamar, Samaa S; Mirdad, Rasha; AlGilban, Hussah M; Haidara, Mohamed A; Abbas, Amr M; Dawood, Amal F.

Int. j. morphol; 40 (1), 2022

SUMMARY: Rheumatoid arthritis (RA), an inflammatory autoimmune disease that causes cartilage degradation and tissue destruction, can affect synovial joints such as the knee joint. The link between the nitrosative stress enzyme inducible nitric oxide synthase (iNOS) and the cytokine interleukin-1 (IL-1 ...

Artritis Reumatoide/inmunología, Glucógeno Sintasa Quinasa 3 beta/antagonistas & inhibidores, Tiadiazoles/administración & dosificación, Glucógeno Sintasa Quinasa 3 beta/administración & dosificación, Estrés Nitrosativo/efectos de los fármacos, Interleucina-1beta, Colágeno Tipo II/administración & dosificación, Ratas Wistar, Artritis Reumatoide/inducido químicamente, Inmunohistoquímica, Modelos Animales de Enfermedad, Inflamación

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Efeitos do ultra-som na hiperalgesia e no edema de ratos artriticos

Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats

Com o envelhecimento populacional a prevalencia de doencas osteomusculares cronicas, que restringem a capacidade funcional dos idosos tem aumentado. A artrite reumatoide, integrante desse grupo de patologias, tem atualmente a sua abordagem terapeutica realizada atraves de medicamentos e de fisioterapia. ...