Clinical characteristics of patients with cerebellar ataxia associated with anti-GAD antibodies
Arq. neuropsiquiatr; 75 (3), 2017
ABSTRACT The enzyme glutamic acid decarboxylase (GAD), present in GABAergic neurons and in pancreatic beta cells, catalyzes the conversion of gamma-aminobutyric acid (GABA). The cerebellum is highly susceptible to immune-mediated mechanisms, with the potentially treatable autoimmune cerebellar ataxia ass...
Autoanticuerpos/sangre, Ataxia Cerebelosa/complicaciones, Ataxia Cerebelosa/diagnóstico, Ataxia Cerebelosa/tratamiento farmacológico, Ataxia Cerebelosa/inmunología, Glutamato Descarboxilasa/sangre, Glutamato Descarboxilasa/inmunología, Inmunoglobulinas Intravenosas/uso terapéutico, Imagen por Resonancia Magnética, Estudios Retrospectivos, Resultado del Tratamiento