Background: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. Celiac disease (CD), a treatable autoimmune enteropathy, with varied presentations, may simulate clinically symptoms of IBS. The aim of the present study is to screen for CD in patients with IBS diagnosed based o...
Abstract Background: To assess the prevalence and clinical relevance of anti-Jo-1 autoantibodies in a representative sample of patients with definite dermatomyositis (DM). Methods: This retrospective cohort study took place from 2005 to 2020 and assessed 118 adult patients from a tertiary center who we...
INTRODUCCIÓN: La manifestación extramuscular de las miopatías inflamatorias idiopáticas (MII) es la enfermedad pulmonar intersticial (EPI) y el diagnóstico se basa en autoanticuerpos séricos. Los nuevos anticuerpos específicos y asociados a MII han ayudado a identificar nuevas entidades clínicas ...
Porta, Gilda;
Carvalho, Elisa de;
Santos, Jorge L;
Gama, Jorge;
Borges, Cristian V;
Seixas, Renata B P M;
Ferreira, Alexandre R;
Miura, Irene K;
Silveira, Themis R;
Silva, Luciana R;
Fagundes, Eleonora D T;
Bellomo-Brandao, Maria A;
Sawamura, Regina;
Vieira, Sandra M;
Melere, Melina U;
Marques, Cibele D F;
Pugliese, Renata P;
Danesi, Vera L;
Porta, Adriana;
Marsillac, Marise E;
Valladares, Marcia A;
Menezes, Daniela G;
Kieling, Carlos;
Paula, Mariana N de;
Vasconcelos, Juliana R;
Ferreira, Cristina T;
Perin, Nilza;
Resende, Leonardo R;
Maia, Jussara;
Tommaso, Adriana M A De;
Hessel, Gabriel.
Abstract Objective: This large study with a long-term follow-up aimed to evaluate the clinical presentation, laboratory findings, histological profile, treatments, and outcomes of children and adolescents with autoimmune hepatitis. Methods: The medical records of 828 children and adolescents with autoi...
Anticuerpos Antinucleares/sangre,
Autoanticuerpos/análisis,
Azatioprina/uso terapéutico,
Biopsia con Aguja,
Brasil,
Hepatitis Autoinmune/tratamiento farmacológico,
Hepatitis Autoinmune/inmunología,
Hepatitis Autoinmune/patología,
Inmunoglobulinas/análisis,
Terapia de Inmunosupresión,
Inmunosupresores/uso terapéutico,
Hígado/patología,
Imagen por Resonancia Magnética,
Prednisona/uso terapéutico,
Estudios Retrospectivos,
Análisis de Supervivencia,
Resultado del Tratamiento
Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative...
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/patología,
Autoanticuerpos/análisis,
Antibacterianos/uso terapéutico,
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/diagnóstico por imagen,
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/tratamiento farmacológico,
Biopsia,
Ciclofosfamida/uso terapéutico,
Técnica del Anticuerpo Fluorescente,
Enfermedades Renales/patología,
Glomérulos Renales/patología,
Prednisona/uso terapéutico,
Recurrencia,
Combinación Trimetoprim y Sulfametoxazol/uso terapéutico
Abstract Background/objective: Digital ulcers (DUs) represent a frequent complication of systemic sclerosis (SSc). The aim of this study was to evaluate clinical, serological and capillaroscopy features that are associated with DUs in patients with SSc. Methods: In this bicentric cross-sectional study,...
Cruvinel, Wilson de Melo;
Andrade, Luis Eduardo Coelho;
von Mühlen, Carlos Alberto;
Dellavance, Alessandra;
Ximenes, Antônio Carlos;
Bichara, Carlos David;
Bueno, Cleonice;
Mangueira, Cristóvão Luis Pitangueira;
Bonfá, Eloísa;
Brito, Fabiano de Almeida;
Flumian, Fernanda Bull;
Silva, Glaucielen Gomes da;
Rêgo, Jozelia;
Anjos, Lisiane Maria Ericoni dos;
Slhessarenko, Natasha;
Pasoto, Sandra Gofinet;
Neves, Suzane Pretti Figueiredo;
Valim, Valéria;
Santos, Wilton Silva dos;
Francescantonio, Paulo Luiz Carvalho.
Abstract Background: The V Brazilian Consensus for determination of autoantibodies against cellular constituents on HEp-2 cells, held in Brasilia (DF, Brazil) on August 27, 2016, discussed the harmonization between the Brazilian Consensus on ANA (BCA) guidelines and the International Consensus on ANA Pa...
Abstract Background: To analyze the frequency and clinical relevance of anti-Mi-2 autoantibody in a representative sample of patients with dermatomyositis. Methods: This longitudinal inception cohort study, from 2001 to 2017, included 87 definite adult dermatomyositis. Anti-Mi-2 analysis was performed ...
Las miopatías inflamatorias idiopáticas (MII) conforman un grupo diverso de en-fermedades caracterizadas por lesiones musculares inmunomediadas, que pue-den estar acompañadas de manifestaciones extramusculares.La identificación de autoanticuerpos específicos de miositis (AEM) y asociados a mi...
OBJECTIVE: The anti-PM/Scl autoantibody has been described in patients with scleromyositis. However, there are scant studies evaluating its prevalence and reactivity in dermatomyositis and polymyositis. METHOD: A cross-sectional, single center study evaluating the anti-PM/Scl autoantibody in 85 dermatom...
