LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Biosynthesized silver nanoparticles: are they effective antimicrobials?

BACKGROUND Silver nanoparticles (AgNPs) are increasingly being used in medical applications. Therefore, cost effective and green methods for generating AgNPs are required. OBJECTIVES This study aimed towards the biosynthesis, characterisation, and determination of antimicrobial activity of AgNPs produ...

Membrane permeabilization of colistin toward pan-drug resistant Gram-negative isolates

Mohamed, Yasmine Fathy; Abou-Shleib, Hamida Moustafa; Khalil, Amal Mohamed; El-Guink, Nadia Mohamed; El-Nakeeb, Moustafa Ahmed.

Braz. j. microbiol; 47 (2), 2016

Abstract Pan-drug resistant Gram-negative bacteria, being resistant to most available antibiotics, represent a huge threat to the medical community. Colistin is considered the last therapeutic option for patients in hospital settings. Thus, we were concerned in this study to demonstrate the membrane perm...

Antibacterianos/metabolismo, Membrana Celular/metabolismo, Colistina/metabolismo, Farmacorresistencia Bacteriana Múltiple, Bacterias Gramnegativas/metabolismo, Infecciones por Bacterias Gramnegativas/microbiología, Antibacterianos/farmacología, Membrana Celular/efectos de los fármacos, Permeabilidad de la Membrana Celular, Colistina/farmacología, Bacterias Gramnegativas/efectos de los fármacos, Bacterias Gramnegativas/aislamiento & purificación, Bacterias Gramnegativas/ultraestructura, Infecciones por Bacterias Gramnegativas/tratamiento farmacológico, Pruebas de Sensibilidad Microbiana

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