BACKGROUND The heterologous expression of parasitic proteins is challenging because the sequence composition often differs significantly from host preferences. However, the production of such proteins is important because they are potential drug targets and can be screened for interactions with new lead ...
Abstract Baculoviruses are considered as effective bio pesticides except of being not active under sunlight conditions. The aim of this study is to evaluate the capability of moringa extract to prolong virus activity under Egyptian field conditions especially that Moringa proved to be strong protective m...
Abstract The fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is an important maize pest. Due to the environmental impact and emergence of resistance caused by chemical pesticides and transgenic events, the use of baculoviruses becomes a safe and useful alternative for its cont...
Development of an enhanced bovine viral diarrhea virus subunit vaccine based on E2 glycoprotein fused to a single chain antibody which targets to antigen-presenting cells
Bovine viral diarrhea virus (BVDV) is an important cause of economic losses worldwide. E2 is an immunodominant protein and a promising candidate to develop subunit vaccines. To improve its immunogenicity, a truncated E2 (tE2) was fused to a single chain antibody named APCH, which targets to antigen-prese...
Lepidopteran larvae may be attacked by different viruses, many of which belong to the Baculoviridae family. Whilst studying the ultrastructure of the neck gland in Dione junio larvae we found that in later instars the larvae showed symptoms of attack by two types of virus. The glands were prepared for op...
Os leucócitos polimorfonucleares têm papel crítico na destruiçäo, digestäo de patógenos, geraçäo e regulaçäo do processo inflamatório. Proteínas que säo estocadas dentro dos grânulos citoplasmáticos têm sido implicadas nos mecanismos microbicidas, independentes de oxigênio, bem como na ...
Para investigar o papel biologico dos proto-oncogenes fos (c-fos,fosB, fra-1 e fra-2) e jun (c-jun, junB e junD), nos propusemos a analisar a expressao dos membros destas duas familias genicas durante a organogenese de camundongos e promover a expressao heterologa de cFos e cJun utilizando o sistema de b...
