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Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway

Hui, Jing; Lei, Qi; Ji, Zhi; Zi, Dingjing.
Biol. Res; 55 (), 2022
BACKGROUND: Betahistine is a clinical medication for the treatment of benign paroxysmal positional vertigo (BPPV). Otolin, a secreted glycoprotein with a C-terminal globular domain homologous to the immune complement C1q, has been identified as a biomarker for BPPV. However, the role of complement C1q/TN...
Vértigo Posicional Paroxístico Benigno/tratamiento farmacológico, Betahistina/farmacología, Betahistina/uso terapéutico, Mareo/tratamiento farmacológico, Sistema de Señalización de MAP Quinasas, PPAR gamma, Proteínas Proto-Oncogénicas c-akt
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Subjective benign paroxysmal positional vertigo in patients with osteoporosis or migraine

González-Aguado, Rocío; Domènech-Vadillo, Esther; Álvarez-Morujo de Sande, María Guadalupe; Guerra-Jiménez, Gloria; Domínguez-Durán, Emilio.
Braz. j. otorhinolaryngol. (Impr.); 86 (1), 2020
Abstract Introduction Subjective benign paroxysmal positional vertigo is a form of benign paroxysmal positional vertigo in which during the diagnostic positional maneuvers patients only present vertigo symptoms with no nystagmus. Objective To study the characteristics of subjects with subjective benign...
Vértigo Posicional Paroxístico Benigno/complicaciones, Vértigo Posicional Paroxístico Benigno/tratamiento farmacológico, Vértigo Posicional Paroxístico Benigno/fisiopatología, Betahistina/uso terapéutico, Estudios de Casos y Controles, Trastornos Migrañosos/complicaciones, Trastornos Migrañosos/fisiopatología, Nistagmo Fisiológico/fisiología, Osteoporosis/complicaciones, Osteoporosis/fisiopatología, Modalidades de Fisioterapia, Postura/fisiología, Estudios Prospectivos, Sulpirida/uso terapéutico
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Hearing function after betahistine therapy in patients with Ménière's disease

Tootoonchi, Seyed Javad Seyed; Ghiasi, Samad; Shadara, Parvaneh; Samani, Simin Mirakhor; Fouladi, Daniel Fadaei.
Braz. j. otorhinolaryngol. (Impr.); 82 (5), 2016
ABSTRACT INTRODUCTION: Preventing or reversing hearing loss is challenging in Ménière's disease. Betahistine, as a histamine agonist, has been tried in controlling vertigo in patients with Ménière's disease, but its effectiveness on hearing problems is not known. OBJECTIVE: To examine the effect of...
Audiometría, Betahistina/uso terapéutico, Pérdida Auditiva/tratamiento farmacológico, Pérdida Auditiva/etiología, Agonistas de los Receptores Histamínicos/uso terapéutico, Enfermedad de Meniere/complicaciones, Enfermedad de Meniere/tratamiento farmacológico, Otoscopía, Resultado del Tratamiento
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