LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Identification of High-affinity Novel Targeted Peptides for the Treatment of Human Ovarian Cancer

Sihui, Li; Wenju, Li; Kofi, Arhin Samuel; Yu, Zhao; Linzhi, Yan; Yijie, Chen; Luyi, Li; Ledan, Wang; Jieqiang, Lv.

Prensa méd. argent; 105 (11), 2019

Background: To investigate the potential of the phage display-identified tumor cellbinding peptide as a biomarker of epithelial ovarian cancer using phage display technology. Method: The Ph.D.-7 Phage Display Peptide Library was used to identify the specific conjugated phages with SKOV3 epithelial ovaria...

Bacteriófagos, Carcinoma Epitelial de Ovario/terapia, Biblioteca de Péptidos, Tamizaje Masivo/métodos, Ensayo de Inmunoadsorción Enzimática, Biomarcadores de Tumor, Diagnóstico Precoz, Informe de Investigación, ADN/análisis

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Sheep polyclonal antibody to map Haemonchus contortus mimotopes using phage display library

Buzatti, Andréia; Fernandez, Arnielis Diaz; Arenal, Amilcar; Pereira, Erlán; Monteiro, Alda Lucia Gomes; Molento, Marcelo Beltrão.

Rev. bras. parasitol. vet; 27 (2), 2018

Abstract The aim of this study was to evaluate phage display technology for mapping Haemonchus contortus mimotopes. We screened the PhD-7 Phage Display Peptide Library Kit with a sheep polyclonal antibody against H. contortus. After four rounds of selection, 50 phage peptide clones were selected by biop...

Anticuerpos Antihelmínticos, Haemonchus/genética, Haemonchus/inmunología, Biblioteca de Péptidos, Ovinos

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Reconhecimento molecular na doença de chagas do ponto de vista do parasita e do hospedeiro

Teixeira, André Azevedo Reis.

A doença de Chagas, causada pelo parasita protozoário Trypanosoma cruzi, afeta milhões de pessoas, a maioria delas vivendo na América latina. Apesar dos avanços da medicina e da biotecnologia, ainda existem poucas opções de tratamento para indivíduos com a doença. Assim, é importante compreende...

Elementos Estructurales de las Proteínas/fisiología, Enfermedad de Chagas/diagnóstico, Mapeo Epitopo/métodos, Biblioteca de Péptidos, Enfermedad de Chagas/prevención & control, Bacteriófagos, Western Blotting/métodos, Trypanosoma cruzi/metabolismo, Metodología como un Tema

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Characterization of Leiurus abdullahbayrami (Scorpiones: Buthidae) venom: peptide profile, cytotoxicity and antimicrobial activity

Erdeş, Efe; Doğan, Tuğba Somay; Coşar, İlhan; Danışman, Tarık; Kunt, Kadir Boğaç; Şeker, Tamay; Yücel, Meral; Özen, Can.

J. venom. anim. toxins incl. trop. dis; 20 (), 2014

Background Scorpion venoms are rich bioactive peptide libraries that offer promising molecules that may lead to the discovery and development of new drugs.Leiurus abdullahbayrami produces one of the most potent venoms among Turkish scorpions that provokes severe symptoms in envenomated victims.Methods In...

Escorpiones, Venenos de Escorpión, Péptidos, Electroforesis Capilar, Biblioteca de Péptidos

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