Abstract Sugammadex is a distinctive neuromuscular reversal drug that acts by encapsulating the neuromuscular relaxant molecule and dislodging it from its site of action. Sugammadex has been approved for pediatric patients over 2 years of age. Although arrhythmias have been reported, there is no report o...
Abstract Background Reliable devices that quantitatively monitor the level of neuromuscular blockade after neuromuscular blocking agents' administration are crucial. Electromyography and acceleromyography are two monitoring modalities commonly used in clinical practice. The primary outcome of this study...
The use of neuromuscular blockers has spread over the last decade, reaching different scenarios such is the case of the obstetric patient, in whom their use both in the operating room and in the intensive care unit is considered one of the main challenges for the treating physician. As there is no recent...
Rojas, Verónica;
Romero, Carlos;
Tobar, Daniel;
Alvarez, Evelyn;
Aranda, Rolando;
Bugedo, Guillermo;
Cariqueo, Marcial;
Sepúlveda, M Idalia;
Sánchez, Juan Eduardo;
Tobar, Eduardo.
Background: The appropriate use of analgesia, sedation, neuromuscular blockade and the diagnosis and prevention of delirium (ASBD) are associated with better outcomes in critically ill patients at Intensive Care Unit (ICUs). Aim: To know the practices about analgesia, sedation, delirium, and neuromuscula...
Abstract Introduction: Rhinella schneideri is a toad widely distributed in South America and its poison is characterized by inducing cardiotoxicity and neurotoxicity. Objective: In this work, we investigated pharmacological strategies to attenuate the peripheral neurotoxicity induced by R. schneideri poi...
RESUMEN El bloqueo residual se define como la debilidad muscular postoperatoria producida por un antagonismo incompleto de los relajantes neu-romusculares, siendo sus principales complicaciones las respiratorias. Actualmente, el mejor método de evaluación objetiva del bloqueo neuromuscular es el Tren d...
RESUMEN Objetivo: Proponer estrategias agile para este abordaje integral de la analgesia, sedación, delirium, implementación de movilidad temprana e inclusión familiar del paciente con síndrome de dificultad respiratoria aguda por COVID-19, considerando el alto riesgo de infección que existe entre ...
Analgesia/métodos,
Analgesia/normas,
COVID-19/complicaciones,
COVID-19/tratamiento farmacológico,
Lista de Verificación,
Consenso,
Delirio/diagnóstico,
Delirio/terapia,
Ambulación Precoz,
Unidades de Cuidados Intensivos,
Intubación Intratraqueal/métodos,
Bloqueo Neuromuscular/métodos,
Manejo del Dolor/métodos,
Manejo del Dolor/normas,
Agitación Psicomotora/terapia,
Síndrome de Dificultad Respiratoria/terapia
Abstract Objective: To compare the use of 2 different local anesthetic solution (LAS) volumes of 1.5 mL and 3 mL in retrobulbar block in patients undergoing cataract surgery in terms of anesthesia, akinesia, and pain levels. Methods: 80 patients between 18-90 years old, ASA I-II-III, were included in t...
Abstract Background and objectives: Sugammadex is an alternative pharmacological drug capable of reversing neuromuscular blockades without the limitations that are presented by anticholinesterase drugs. Coagulation disorders that are related to treatment with sugammadex were reported. The exact mechanis...
Anestesia/métodos,
Anestésicos por Inhalación,
Coagulación Sanguínea/efectos de los fármacos,
Combinación de Medicamentos,
Fibrinógeno/análisis,
Isoflurano,
Bloqueo Neuromuscular,
Fármacos Neuromusculares no Despolarizantes/administración & dosificación,
Fármacos Neuromusculares no Despolarizantes/farmacología,
Tiempo de Tromboplastina Parcial,
Recuento de Plaquetas,
Tiempo de Protrombina,
Distribución Aleatoria,
Ratas Wistar,
Rocuronio/administración & dosificación,
Rocuronio/farmacología,
Sugammadex/administración & dosificación,
Sugammadex/farmacología
