Objective: To synthesize evidence involving pathophysiological and clinical-epidemiological linking mechanisms in women with breast cancer and metabolic syndrome. Method: This is a structured scoping review according to the Joanna Briggs Institute and was conducted in the PubMed, BDENF, LILACS, IB...
Aumento de Peso,
Ciencia,
Ciencias de la Nutrición,
Células,
Dieta,
Enfermedad,
Ejercicio Físico,
LILACS,
Mama,
Mujeres,
Métodos,
Músculos,
Neoplasias,
Neoplasias de la Mama,
Obesidad,
Pacientes,
Investigación,
Pronóstico,
PubMed,
Recurrencia,
Pérdida de Peso,
Riesgo,
Síndrome Metabólico,
Tejido Adiposo,
Terapéutica,
Quimioterapia
Aim: Venous blood derivatives (VBDs) have been suggested as substitutes for Fetal Bovine Serum (FBS) to improve the clinical transition of cell-based therapies. The literature is not clear about which is the best VBDs substitute. The present study aimed to evaluate the influence of VBDs on cell viability...
Abstract Glioblastoma multiforme is a tumor of the central nervous system. Focal Adhesion Kinase (FAK) and αB-crystalline are two proteins involved in glioblastoma development. In this study, we investigated whether the FAK/αB-crystalline interaction is important for glioblastoma cells, we aimed to inv...
A quimioinformática, definida como o emprego de técnicas informáticas na solução de problemas da química, evolui em conjunto com o desenvolvimento de ferramentas computacionais e é de grande relevância para o planejamento racional de fármacos ao otimizar etapas do desenvolvimento de novas moléc...
Aminoácidos/agonistas,
Asparagina/análogos & derivados,
d0487880,
Células/clasificación,
ADN/efectos adversos,
d0151950,
d0199840,
d0080240,
Neoplasias/patología,
ddcs0518460,
Preparaciones Farmacéuticas/análisis,
Quimioinformática/instrumentación
A via Hippo consiste em uma cascata de serina-treonina quinases que desempenha um papel central na transdução de sinais mecânicos. Em mamíferos, o eixo canônico da via consiste na ativação das quinases MST1 e MST2 (codificadas pelos genes STK4 e STK3, respectivamente) e LATS1 e LATS2. A ativação...
Introduction: the use of light emitting diodes (LED) in domestic and public vias have increased in the last 20 years. In addition, the LED light has been used as a light source for medical applications. Objective: since humans are increasingly exposed to LEDs, there is an urgency to investigate the poss...
Abstract Lung cancer is a major cause of cancer-related death worldwide. This study investigated the regulatory effects of the microRNA-99a-5p (miR-99a-5)/VLDLR axis on lung cancer cell sensitivity to chemotherapy and its mechanism. miR-99a-5p and VLDLR expression levels were quantified using RT-qPCR and...
Worldwide, leptospirosis is the most highly prevalent
zoonosis. Although the wide range of clinical manifestations of
leptospirosis in humans is well-documented, knowledge of the
mechanisms through which this pathogen causes kidney disease
remains limited. This narrative review of the scientific literatu...
Resumen Escherichia coli shigatoxigénica (STEC) está involucrada en el desarrollo del síndrome urémico hemolítico, entre otras enfermedades que son de gran importancia para la salud pública e inocuidad alimentaria a nivel mundial. La capacidad de STEC de formar biofilms en los alimentos y en difere...
Contaminación Ambiental,
Crecimiento y Desarrollo,
Escherichia coli,
Escherichia coli Shiga-Toxigénica,
Enfermedad,
Alimentos,
Biopelículas,
Células,
Esguinces y Distensiones,
Genes,
Inocuidad de los Alimentos,
Métodos
Resumen El presente comentario, escrito en virtud del decreto del gobierno nacional que designó a 2021 como año de homenaje al Dr. César Milstein, es una visión personal sobre el significado del desarrollo de los anticuerpos monoclonales, del aporte que brindó y brinda a la ciencia y tecnología act...
Anticuerpos Monoclonales,
Alergia e Inmunología,
Ciencia,
Conocimiento,
Crecimiento y Desarrollo,
Células,
Especialización,
Grupos Profesionales,
Tecnología,
Visión Ocular,
Premio Nobel,
Personajes
