Transplantation and survival of mouse inner ear progenitor/stem cells in the organ of Corti after cochleostomy of hearing-impaired guinea pigs: preliminary results
Braz. j. med. biol. res; 49 (4), 2016
In mammals, damage to sensory receptor cells (hair cells) of the inner ear results in permanent sensorineural hearing loss. Here, we investigated whether postnatal mouse inner ear progenitor/stem cells (mIESCs) are viable after transplantation into the basal turns of neomycin-injured guinea pig cochleas....
Umbral Auditivo, Supervivencia Celular, Células Cultivadas, Potenciales Evocados Auditivos del Tronco Encefálico, Cobayas, Células Ciliadas Auditivas Internas/trasplante, Pérdida Auditiva Sensorineural/cirugía, Inmunohistoquímica, Ratones Endogámicos BALB C, Neomicina, Órgano Espiral/cirugía, Inhibidores de la Síntesis de la Proteína, Reproducibilidad de los Resultados, Trasplante de Células Madre/métodos, Células Madre, Resultado del Tratamiento