Results: 2

Neuroprotective effects of erythropoietin on rat retinas subjected to oligemia

Clinics; 73 (), 2018
OBJECTIVES: Erythropoietin may have neuroprotective potential after ischemia of the central nervous system. Here, we conducted a study to characterize the protective effects of erythropoietin on retinal ganglion cells and gliotic reactions in an experimentally induced oligemia model. METHODS: Rats were ...

Rescuing axons from degeneration does not affect retinal ganglion cell death

Braz. j. med. biol. res; 49 (4), 2016
After a traumatic injury to the central nervous system, the distal stumps of axons undergo Wallerian degeneration (WD), an event that comprises cytoskeleton and myelin breakdown, astrocytic gliosis, and overexpression of proteins that inhibit axonal regrowth. By contrast, injured neuronal cell bodies sho...