The effects of systemic insulin administration at different concentrations on the testicular tissue of diabetic adult rats, induced by streptozotocin, are evaluated by the morphological analysis of spermatogenic process. Twenty-four adult male rats were divided into 1) Control Group: they received citrat...
ABSTRACT We report a 27 -year-old male referred because of hypergonadotropic hypogonadism with low testosterone and azoospermia. At 23 years of age, he underwent an excision of a hypoechoic 0.7 cm nodule of the left testicle. The pathological diagnosis was a Leydig cell tumor. In the right testicle, ther...
La reserpina es un antipsicótico e hipotensor arterial que reduce significativamente los niveles de monoaminas centrales, y también es utilizada para modelar los cuadros depresivos humanos en animales de laboratorio. Este trabajo estudió, en ratas Wistar machos adolescentes, cómo la reserpina afecta ...
Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and intracellular calcium storages recruited by a calci...
Potenciales de Acción,
Adenosina Trifosfato/fisiología,
Arginina/administración & dosificación,
Arginina/metabolismo,
Células Cultivadas,
GMP Cíclico/administración & dosificación,
GMP Cíclico/análogos & derivados,
GMP Cíclico/metabolismo,
Células Intersticiales del Testículo/fisiología,
NG-Nitroarginina Metil Éster/administración & dosificación,
NG-Nitroarginina Metil Éster/metabolismo,
Óxido Nítrico/biosíntesis,
Óxido Nítrico/fisiología,
Técnicas de Placa-Clamp,
Receptores Purinérgicos/metabolismo,
Tionucleótidos/administración & dosificación,
Tionucleótidos/metabolismo
Abstract Purpose: To analyze the effects of aging in rats on the nuclear volume, cytoplasmic volume, and total volume of Leydig cells, as well as their number. Methods: Seventy-two Wistar rats were divided into six subgroups of 12 rats, which underwent right orchiectomy at 3, 6, 9, 12, 18, and 24 mont...
ABSTRACT The germinative, Sertoli and Leydig cells of two caviomorph rodents (Cavia porcellus and Dasyprocta agouti) were counted as well as the estimation of the total volume of the testis and the total volume of seminiferous tubules and interstitium in prepubertal, pubertal and adult animals. The numbe...
Zhang, Tianxiang;
Peng, Dong;
Qi, Lei;
Li, Weixuan;
Fan, Mengyuan;
Shen, Jiachen;
Yang, Liangliang;
Wang, Yihua;
Wang, Wenxia;
Hu, Xiaolong;
Cai, Ruibo;
Zhou, Ran;
Wei, Yuting;
Zhou, Juntong;
Yang, Shuang;
Hu, Defu;
Liu, Shuqiang.
BACKGROUND: The muskrat is a seasonal breeder. Males secrete musk to attract females during the breeding season. The testosterone binding to the androgen receptor (AR) in musk glands of muskrat may play an important role conducting the musk secretion process. METHODS: The musk gland, testis and blood sam...
Ácidos Grasos Monoinsaturados/metabolismo,
Glándulas Odoríferas/crecimiento & desarrollo,
Glándulas Odoríferas/metabolismo,
Testículo/metabolismo,
Ácidos Grasos Monoinsaturados/análisis,
Células Intersticiales del Testículo/metabolismo,
Receptores Androgénicos/análisis,
Receptores Androgénicos/metabolismo,
Reproducción/fisiología,
Glándulas Odoríferas/anatomía & histología,
Testículo/crecimiento & desarrollo,
Testosterona/sangre,
Arvicolinae,
Western Blotting,
Cruzamiento,
Ensayo de Inmunoadsorción Enzimática,
Inmunohistoquímica,
Tamaño de los Órganos,
Valores de Referencia,
Estaciones del Año,
Análisis de Secuencia de ARN
