Results: 3

Long-term resveratrol administration improves diabetes-induced pancreatic oxidative stress, inflammatory status, and β cell function in male rats

Abstract Diabetes is a metabolic disorder caused by insulin resistance or a defect in the pancreatic beta cells in insulin secretion. The aim of this study was to evaluate the possible effectiveness of long-term administration of resveratrol on inflammatory and oxidative stress markers in the pancreatic...

Mecanismos moleculares mediadores da citoproteção de células beta pancreáticas induzidos por prolactina

A manutenção da célula de ilhotas in vitro aparece como uma estratégia atraente para aumentar o resultado do transplante de ilhotas pancreáticas. Entretanto, o destino das ilhotas em cultura é determinado pelo equilíbrio entre mediadores pró e antiapoptóticos. Nós mostramos anteriormente que os...

Pancreatic beta cell protection/regeneration with phytotherapy

Braz. j. pharm. sci; 51 (1), 2015
Although currently available drugs are useful in controlling early onset complications of diabetes, serious late onset complications appear in a large number of patients. Considering the physiopathology of diabetes, preventing beta cell degeneration and stimulating the endogenous regeneration of islets w...