Results: 6

Study of Cerebellar Tissue Following Induction of Aging in Mice By Di-Galactose

Int. j. morphol; 41 (3), 2023
SUMMARY: The cerebellum is a crucial area of the hindbrain that plays an essential role in balancing, excitement control, and subtle and accurate functions. Studies have shown that long-term use of D-galactose in mice, as with the symptoms of aging, causes morphological and functional disorders in the br...

Effects of prenatal tobacco smoke on cerebellum histomorphological changes at critical developmental stages in CD-1 mice

Int. j. morphol; 39 (1), 2021
SUMMARY: In this study the consequences of prenatal exposure to tobacco smokes on the histo-morphological changes of cerebellum was assessed by comparing the smoker mice to the nonsmoker mice. A total of 30 pregnant cd-1 mice were divided into three groups of 10 mice each and with two replicates per grou...

Jan Evangelista Purkinje, a brilliant, multifaceted Czech biologist: nerve tissue

Rev. bras. neurol; 55 (4), 2019
Jan Evangelista Purkinje was a Czech physician with an exceptional capacity for innovative thinking, and he was one of the fathers of experimental physiology, experimental pharmacology, experimental psychology, histology, embryology, and physical anthropology. Several achievements are named after him, f...

Cerebellar synaptopathy in streptozotocin-induced diabetic rats

Int. j. morphol; 37 (1), 2019
SUMMARY: There is an increasing amount of evidence that supports the diabetic complications of the central nervous system structure and function. The cerebellum, which is one of the primary structure derived from the hindbrain, plays an important role in motor control, motor coordination, and non-motor f...

Effect of gestational diabetes on neuronal cells in rat cerebellum in early postnatal life

Int. j. morphol; 32 (2), 2014
Previous study has shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on rat cerebellum in early postnatal life. In this experimental study, 10 dams randomly allocated into control and...

Diferenciação de células-tronco embrionárias murinas (mESCs) em células produtoras de insulina (IPCs) e caracterização funcional do gene Purkinje cell protein 4 (Pcp4) neste processo

Fontes alternativas de células β têm sido estudadas para o tratamento de Diabetes mellitus tipo 1, dentre as quais a mais promissora consiste das células-tronco diferenciadas em células produtoras de insulina (IPCs). Alguns trabalhos demonstram a capacidade de células-tronco embrionárias murinas (...