LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Bone callus formation is highly disrupted by dietary restriction in growing rats sustaining a femoral fracture

Botega, Iara Inácio; Zamarioli, Ariane; Guedes, Patrícia Madalena San Gregório; Silva, Raquel Assed Bezerra da; Issa, João Paulo Mardegan; Butezloff, Mariana Maloste; Sousa, Yara Terezinha Corrêa Silva; Ximenez, João Paulo Bianchi; Volpon, José Batista.

Acta cir. bras; 34 (1), 2019

Abstract Purpose: To evaluate the effects of food restriction on fracture healing in growing rats. Methods: Sixty-eight male Wistar rats were assigned to two groups: (1) Control and (2) Dietary restriction. After weaning the dietary restricted animals were fed ad libitum for 42 days with 50% of the s...

Densidad Ósea/fisiología, Callo Óseo/fisiología, Fracturas del Fémur/diagnóstico por imagen, Fracturas del Fémur/fisiopatología, Fijación Intramedular de Fracturas, Curación de Fractura/fisiología, Fracturas Cerradas/diagnóstico por imagen, Fracturas Cerradas/fisiopatología, Desnutrición, Osteoporosis/prevención & control, Ratas Wistar

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Nandrolone decanoate appears to increase bone callus formation in young adult rats after a complete femoral fracture

Abstract Purpose: To evaluate the influence of nandrolone decanoate on fracture healing and bone quality in normal rats. Methods: Male rats were assigned to four groups (n=28/group): Control group consisting of animals without any intervention, Nandrolone decanoate (DN) group consisting of animals tha...