Histomorphometric analysis of liver biopsies of treated patients with Gaucher disease type 1
Autops. Case Rep; 11 (), 2021
Gaucher disease (GD) is an autosomal recessive lysosomal disorder caused by a disturbance in the metabolism of glucocerebroside in the macrophages. Most of its manifestations - hepatosplenomegaly, anemia, thrombocytopenia, and bone pain - are amenable to a macrophage-target therapy such as enzyme replace...