In vitro/in vivo performance of different complexes of itraconazole used in the treatment of vaginal candidiasis
Braz. j. pharm. sci; 48 (4), 2012
A large majority of new chemical entities and many existing drug molecules exhibit poor aqueous solubility, which may limit their potential use in developing drug formulations, with optimum bioavailability. One of the approaches to improve the solubility of a poorly water soluble drug and eventually its ...