LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Biopsias endoscópicas en la era de la inmunoterapia y oncogenética: ¿podemos cumplir los requerimientos?

Donoso Guillén, Felipe; Orellano, D.

Gastroenterol. latinoam; 35 (2), 2024

Pancreatic ductal adenocarcinoma has increased its incidence in recent years. In approximately half of the cases, the diagnosis is made when the disease is in the metastatic stage. In advanced stages, treatment with immunotherapy is included with promising results. Histopathological diagnosis is required...

Neoplasias Pancreáticas/patología, Carcinoma Ductal Pancreático/patología, Endoscopía Gastrointestinal/métodos, Biopsia/métodos, Neoplasias Pancreáticas/genética, Inmunoterapia, Neoplasias Pancreáticas/tratamiento farmacológico, Carcinoma Ductal Pancreático/tratamiento farmacológico, Carcinoma Ductal Pancreático/genética

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A pancreatic mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) (NET and undifferentiated carcinoma of the pancreas with osteoclast-like giant cells) with metastatic neuroendocrine component to the liver

Gao, Guofeng; Qorbani, Amir; Zhou, Chihong Heidi.

Autops. Case Rep; 11 (), 2021

Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (UCOGCs) is an extremely rare morphologically and clinically distinct variant of pancreatic ductal adenocarcinoma (PDAC), exhibiting a characteristic component of reactive osteoclast-like giant cells admixed with neoplastic monon...

Neoplasias Pancreáticas/patología, Células Gigantes, Tumores Neuroendocrinos, Carcinoma Ductal Pancreático/patología, Resultado Fatal

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CCAT2 is an oncogenic long non-coding RNA in pancreatic ductal adenocarcinoma

Cai, Yi; Li, Xiaomei; Shen, Peng; Zhang, Dong.

Biol. Res; 51 (), 2018

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is highly aggressive with poor prognosis. Long non-coding RNAs (lncRNAs), a group of non-coding RNAs, play important roles in the progression of PDAC. This study aimed to investigate the potential involvement of lncRNA CCAT2 in PDAC tumorigenes...

Carcinoma Ductal Pancreático/genética, Mutación/genética, Proteínas Proto-Oncogénicas p21(ras)/genética, ARN Largo no Codificante/genética, Carcinoma Ductal Pancreático/patología, Estadificación de Neoplasias, Pronóstico, Reacción en Cadena en Tiempo Real de la Polimerasa

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Análise da expressão de RNAs não codificadores longos em adenocarcinoma de pâncreas

Tahira, Ana Carolina.

RNAs não codificadores longos (lncRNAs) compõem uma fração significativa do transcriptoma. Alterações na expressão de lncRNAs já foram observadas em vários cânceres humanos, mas ainda não foram exploradas no adenocarcinoma pancreático ductal (PDAC), uma doença devastadora e agressiva para a ...

Perfilación de la Expresión Génica/instrumentación, Expresión Génica/genética, Análisis de Secuencia por Matrices de Oligonucleótidos, Simulación por Computador/22074, Biología Molecular, Transcriptoma/genética, ARN Largo no Codificante/análisis, Carcinoma Ductal Pancreático/patología

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