LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Identification of a subtype of poorly differentiated invasive ductal carcinoma of the breast based on vimentin and e-cadherin expression

Orlandini, Leonardo Fleury; Reis, Francisco José Cândido dos; Silveira, Willian Abraham da; Tiezzi, Marcelo Guimarães; Andrade, Jurandyr Moreira de; Ribeiro-Silva, Alfredo; Deaton, Ryan; Bosland, Maarten; Tiezzi, Daniel Guimarães.

Rev. bras. ginecol. obstet; 40 (12), 2018

Abstract Objective The use of molecular markers can identify a subgroup of tumors with distinct recurrence patterns. The present study aimed to characterize the immunohistochemical expression of vimentin (VIM), of E-cadherin (CDH1), and of cytokeratin 5 (CK5) in patients with invasive ductal carcinomas...

Neoplasias de la Mama/química, Neoplasias de la Mama/clasificación, Neoplasias de la Mama/metabolismo, Neoplasias de la Mama/patología, Cadherinas/análisis, Cadherinas/biosíntesis, Carcinoma Ductal de Mama/química, Carcinoma Ductal de Mama/clasificación, Carcinoma Ductal de Mama/metabolismo, Carcinoma Ductal de Mama/patología, Inmunohistoquímica, Queratina-5/análisis, Queratina-5/biosíntesis, Persona de Mediana Edad, Vimentina/análisis, Vimentina/biosíntesis

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Evaluation of survivin immunoexpression in the differentiation of high- and low-grade breast ductal carcinoma in situ

Chade, Milca Cezar; Piato, Sebastião; Galvão, Maria Antonieta Longo; Aldrighi, José Mendes; Negrini, Rômulo; Mateus, Evandro Falaci; Medeiros, Enio Martins.

Einstein (Säo Paulo); 16 (1), 2018

ABSTRACT Objective To evaluate the expression of survivin protein in low- and high-grade ductal carcinoma in situ. Methods Breast tissue fragments obtained by incisional biopsy and surgical procedures of 37 women with ductal carcinoma in situ of the breast were subdivided into two groups: Group A, comp...

Biomarcadores de Tumor/metabolismo, Neoplasias de la Mama/metabolismo, Neoplasias de la Mama/patología, Carcinoma in Situ/metabolismo, Carcinoma in Situ/patología, Carcinoma Ductal de Mama/metabolismo, Carcinoma Ductal de Mama/patología, Inmunohistoquímica, Proteínas Inhibidoras de la Apoptosis/metabolismo, Survivin

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Schirrous invasive ductal carcinoma of the breast overexpress p53 oncoprotein

Ferrini, Flávia Silva; Rossi, Marcos Antonio; Mouräo Neto, Mário; Soares, Fernando Augusto.

Säo Paulo med. j; 119 (1), 2001

CONTEXT: Breast cancer is the most important neoplasm in adult women, and its worldwide incidence is growing. The tumoral stroma is very important for modulating the growth and invasion of the tumor itself. The relationship between these two components is not completely understood. Schirrous carcinoma is...

Neoplasias de la Mama/patología, Proteína p53 Supresora de Tumor/metabolismo, Receptor ErbB-2/metabolismo, Carcinoma Ductal de Mama/patología, Carcinoma Ductal de Mama/metabolismo, Neoplasias de la Mama/metabolismo, Biomarcadores de Tumor/metabolismo, Proteínas de Neoplasias/metabolismo, Estudios Retrospectivos

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Microrregiões metabólicas no carcinoma ductal infiltrativo de mama humana

Santos, Bianca Maria Alves dos.

No presente estudo analisou-se o metabolismo de glicose e glutamina, através da determinação da atividade enzimática, em carcinomas ductais infiltrativos de pacientes sem tratamento. As pacientes estavam na faixa etária entre 32 e 68 anos e cerca de 75 por cento no período pós-menopausa. Os tumore...

Neoplasias de la Mama/metabolismo, Carcinoma Ductal de Mama/metabolismo, Glutamina/biosíntesis, Insulina/biosíntesis, Piruvato Quinasa, Línea Celular, Cromatografía