ABSTRACT Objective: To identify the clinicopathological correlation of E-cadherin expression in metastatic and non-metastatic oral squamous cell carcinoma (OSCC). Material and Methods: A total of 90 paraffin-embedded tissue sections of OSCC were retrieved from the registry. The total selected samples w...
O carcinoma de células escamosas de língua oral (CCELO) apresenta altas taxas de
morbidade e mortalidade. Apesar dos progressos alcançados nesta área, os
pesquisadores continuam em busca de biomarcadores moleculares que tenham valor
preditivo no prognóstico dos pacientes e que possibilitem o desenvo...
Vía de Señalización Hippo,
Lengua/lesiones,
Carcinoma de Células Escamosas de Cabeza y Cuello/patología,
Proteínas Señalizadoras YAP/metabolismo,
Pronóstico,
Distribución de Chi-Cuadrado,
Análisis de Supervivencia,
Estudio Observacional,
Estudios Transversales/métodos,
Estudios Retrospectivos,
Interpretación Estadística de Datos,
Registros Médicos
ABSTRACT: The most widely used method to classify prognostic factors in cancers today is TNM. However, Oral Squamous Cell Carcinoma (OSCC) often demonstrates different behaviors in relation to aggressiveness and therapeutic response at the same TNM stage. So, in such cases biomarkers can be used to ident...
Spindle cell squamous cell carcinoma (SpSCC) is a rare biphasic malignant neoplasm, uncommonly affecting the oral cavity. The SpSCC diagnosis is difficult, especially when it exhibits inconspicuous morphology, inadequate tissue sampling, or association with an exuberant inflammatory reaction. Post-radiot...
Introduction Squamous carcinoma is the commonest malignancy of the head and neck region. It is associated with high morbidity and mortality. Epidermal growth factor receptor (EGFR) regulates downstream signaling pathways through its tyrosine kinase (TK) domains that play a role in cell proliferation and ...
ABSTRACT Objective: To determine the association of socio-demographic and clinic-pathological risk factors with oral cancer in Kelantan, Malaysia. Material and Methods: A 19-year cross-sectional survey was performed in Hospital Universiti Sains Malaysia (HUSM), Malaysia. Medical record of 301 oral canc...
Neoplasias de las Glándulas Salivales/patología,
Estudios Retrospectivos,
Estudios Transversales,
Factores de Riesgo,
Neoplasias de la Boca/patología,
Registros Médicos,
Carcinoma de Células Escamosas de Cabeza y Cuello/patología,
Carcinoma de Células Escamosas/patología,
Neoplasias de la Lengua/patología,
Epidemiología Descriptiva,
Malasia/epidemiología
ABSTRACT: Many areas of South America are directly affected by Arsenic (As) contaminated groundwater. A high percentage of the water samples taken in multiple areas of Argentina had As concentrations above the WHO level recommended guidelines. This condition was previously associated with an increased ri...
O carcinoma de células escamosas (CCE) é a neoplasia maligna mais frequente da cavidade oral e apresenta prognóstico desfavorável. Assim sendo, pesquisas têm buscado esclarecer o papel de biomarcadores no comportamento biológico do CCE oral. Nesta perspectiva, destacam-se o ativador de plasminogên...
Inmunohistoquímica/métodos,
Carcinoma de Células Escamosas de Cabeza y Cuello/patología,
Activador de Plasminógeno de Tipo Uroquinasa,
Inactivadores Plasminogénicos,
Proteínas Recombinantes/inmunología,
Neoplasias,
Técnicas In Vitro/métodos,
Técnicas de Cultivo de Célula/métodos,
Distribución de Chi-Cuadrado,
Análisis de Supervivencia,
Estadísticas no Paramétricas,
Células Tumorales Cultivadas
Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors. Ethanol extract of Antrodia cinnamomea (EEA) has been widely studied for its health benefits including anticancer effects. The purpose of this study was to assess the effects of EEA on HNSCC. Cell proliferation, tra...
Antrodia/química,
Apoptosis/efectos de los fármacos,
Productos Biológicos/farmacología,
Western Blotting,
Línea Celular Tumoral,
Proliferación Celular/efectos de los fármacos,
Etanol/aislamiento & purificación,
Etanol/farmacología,
Neoplasias Pulmonares/tratamiento farmacológico,
Neoplasias Pulmonares/patología,
Ratones Endogámicos BALB C,
Carcinoma de Células Escamosas de Cabeza y Cuello/tratamiento farmacológico,
Carcinoma de Células Escamosas de Cabeza y Cuello/patología,
Factores de Tiempo
Abstract Oral and oropharyngeal cancer is considered a public health problem in several countries due to its high incidence and mortality rate. Objective: This study aimed to analyze oral and oropharyngeal cancer mortality in Uruguay from 1997 to 2014 by age, sex and country region. Methodology: A time...
Distribución por Edad,
Incidencia,
Neoplasias Orofaríngeas/mortalidad,
Neoplasias Orofaríngeas/patología,
Factores de Riesgo,
Distribución por Sexo,
Carcinoma de Células Escamosas de Cabeza y Cuello/mortalidad,
Carcinoma de Células Escamosas de Cabeza y Cuello/patología,
Factores de Tiempo,
Neoplasias de la Lengua/mortalidad,
Neoplasias de la Lengua/patología,
Uruguay/epidemiología
