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Zofenopril antitumor activity in mice bearing Ehrlich solid carcinoma: Modulation of PI3K/AKT signaling pathway

Mansour, Suzan Mohamed; Ibrahim, Rasha Youssef Mohammed.
Braz. J. Pharm. Sci. (Online); 58 (), 2022
Angiotensin-II (AgII) is thought to be crucial for tumor growth and progression. Moreover, hydrogen sulfide (H2S) performs a controversial action in cancer pathology. Zofenopril (ZF) is an angiotensin-converting enzyme (ACE) inhibitor with H2S donating properties. Hence, this study aims at investigating ...
Carcinoma de Ehrlich/patología, Angiotensina II/efectos adversos, Carcinoma/patología, Expresión Génica, Factor A de Crecimiento Endotelial Vascular, Neoplasias
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Effect of Thyroxine and Propylthiouracil in Ehrlich Ascitic Tumor Cells

Freitas, E. S; Leite, E. D; Silva, A. E; Ocarino, N. M; Ferreira, E; Gomes, M. G; Cassali, G. D; Serakides, R.
Int. j. morphol; 24 (4), 2006
The main purpose of this study was to investigate the effect of thyroxine and PTU in ascitic Ehrlich tumor cells. Tumor was implanted in 30 female mice distributed in three groups: treated with PTU, treated with thyroxine and control. Each group received an intraperitoneal injection of neoplastic cells, ...
Carcinoma de Ehrlich/patología, Tiroxina/farmacología, Propiltiouracilo/farmacología, Tiroxina/administración & dosificación, Propiltiouracilo/administración & dosificación, Región Organizadora del Nucléolo, Línea Celular Tumoral/efectos de los fármacos, Inyecciones Intraperitoneales
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An experimental study on the lymphatic dissemination of the solid Ehrlich tumor in mice
Estudo experimental sobre a disseminaçäo linfática do tumor de Ehrlich na forma sólida em camundongos

Dagli, Maria Lúcia Zaidan; Guerra, José Luiz; Saldiva, Paulo Hilário Nascimento.
Braz. j. vet. res. anim. sci; 29 (1), 1992
As metástases para linfonodos regionais representam fase importante na disseminaçäo neoplásica. Os mecanismos que concorrem para este processo säo pouco conhecidos, devido provavelmente à escassez de modelos experimentais adequados. O objetivo do presente estudo é o de caracterizar o tumor de Ehrl...
Carcinoma de Ehrlich/patología