Morphometric analysis and pattern of protein and gene expression of apoptosis in focal cerebral ischemia in rats and the neuroprotetive action of hypothermia and ketoprofen
Int. j. morphol; 38 (3), 2020
This study aimed to investigate the morphometric and the pattern of protein and gene expression related to the extrinsic apoptotic pathway in experimental focal cerebral ischemia and the hole of neuroprotection with hypothermia and ketoprofen. For this analysis, 120 rats were randomly divided into 3 grou...
Isquemia Encefálica/terapia, Isquemia Encefálica/genética, Apoptosis/genética, Hipotermia Inducida, Cetoprofeno/farmacología, Fármacos Neuroprotectores/farmacología, Isquemia Encefálica/patología, Caspasa 8/genética, Caspasa 3/genética, Modelos Animales de Enfermedad, Inmunohistoquímica, Isquemia Encefálica/metabolismo, Reacción en Cadena en Tiempo Real de la Polimerasa