Bosanac, Milana;
Amidzic, Jelena;
Stefanovic, Maja;
Radic, Jelena;
Kolarov-Bjelobrk, Ivana;
Janicic, Stefan;
Gojkovic, Zdenka;
Lazic, Bojana;
Djokanovic, Dejan;
Misan, Aleksandra;
Cvetkovic, Biljana;
Stupar, Alena;
Martic, Nikola;
Andrejic-Visnjic, Bojana.
SUMMARY: Doxorubicin (DOX) is one of the drugs necessary for the treatment of the 10 most common types of cancer. The leading adverse effect limiting clinical use of DOX is cardiotoxicity. Given that literature data indicate a protective role of carotenoids in doxorubicin-induced toxicity, in our study w...
Cardiotoxicidad/prevención & control,
Cucurbita/química,
Carotenoides/administración & dosificación,
Doxorrubicina/toxicidad,
Antibióticos Antineoplásicos/toxicidad,
Neoplasias/tratamiento farmacológico,
Peroxidación de Lípido,
Catalasa,
Glutatión Transferasa,
Glutatión Peroxidasa,
Ratas Wistar,
Antioxidantes,
Estrés Oxidativo/efectos de los fármacos,
Cardiotónicos
Abstract Telomerase enzyme is necessary for the elongation of telomeres while telomerase being critical for aging and cancer. Metformin, ibuprofen, and acetylsalicylic acid used in this research are drugs that millions of people already use and that many are likely to use in future. In this study, the ef...
ABSTRACT Mastitis is one of the most important illnesses in specialized dairy herds worldwide due to the effects on production and animal health. The types caused by CNS has a special importance in a production where the main pathogens are controlled. The objective of the present work is to determine the...
Mastitis,
Staphylococcus,
Células,
Bovinos,
Glándulas Mamarias Animales,
Electroforesis,
Estudios Longitudinales,
Medicina Veterinaria,
Prevalencia,
Recuento de Células,
Bacilos Grampositivos,
Hemólisis,
Catalasa
SUMMARY: The aim of this study was to determine the relationship of autophagy-enhancing rapamycin (RAPA) and autophagy- inhibitor 3-methyladenine (3-MA) with Nitric oxide synthases (NOS) in Cisplatin (CIS)-induced neurotoxicity in rats. Rats were divided into 4 groups (n=10): Control was applied saline, ...
Síndromes de Neurotoxicidad,
Sirolimus/farmacología,
Adenina/análogos & derivados,
Adenina/farmacología,
Óxido Nítrico Sintasa/efectos de los fármacos,
Cisplatino/toxicidad,
Antineoplásicos/toxicidad,
Ratas Wistar,
Inmunohistoquímica,
Superóxido Dismutasa,
Catalasa,
Malondialdehído,
Interleucina-6,
Ensayo de Inmunoadsorción Enzimática
Resumo Fundamento O treino de força tem efeitos benéficos em doenças renais, além de ajudar a melhorar a defesa antioxidante em animais saudáveis. Objetivo Verificar se o treino de força reduz o dano oxidativo ao coração e rim contralateral para cirurgia de indução de hipertensão renovascu...
SUMMARY: Bisphenol A (BPA) is an industrial chemical widely used to make polycarbonate plastics for packaging and epoxy resins. This study sought to examine how selenium (Se) affects BPA toxicity in terms of albino rats' histological structure, antioxidant enzymes and reproductive organs (seminiferous tu...
Selenio/farmacología,
Antioxidantes/farmacología,
Compuestos de Bencidrilo/toxicidad,
Testículo/efectos de los fármacos,
Apoptosis/efectos de los fármacos,
Administración Oral,
Fenoles/toxicidad,
Testículo/patología,
Superóxido Dismutasa/efectos de los fármacos,
Glutatión Peroxidasa/efectos de los fármacos,
Microscopía Electrónica,
Estrés Oxidativo,
Compuestos de Bencidrilo/administración & dosificación,
Fenoles/administración & dosificación,
Catalasa/efectos de los fármacos,
Biomarcadores
Lactococcus garvieae es una causa inusual de bacteriemia. No existen guías diagnósticas y terapéuticas actuales disponibles para tratar las infecciones causadas por estos organismos. Con base en un informe de caso, proporcionamos una revisión de la literatura sobre bacteriemia causada por L. garvieae...
A nefropatia isquêmica é uma doença renal crônica provocada pela redução do fluxo sanguíneo renal que pode progredir para a doença renal terminal, cujo tratamentos disponíveis se baseiam em terapias substitutivas da função renal, como diálise ou transplante renal. No entanto, devido ao alto c...
Células Madre Mesenquimatosas,
Enfermedades Renales/inducido químicamente,
Riñón/fisiopatología,
Estrés Oxidativo,
Diagnóstico Tardío,
Diagnóstico Precoz,
Catalasa/análisis,
Glutatión Peroxidasa/análisis,
Biomarcadores/análisis,
Carbonilación Proteica,
Hematoxilina,
Reacción del Ácido Peryódico de Schiff/métodos,
Técnica del Anticuerpo Fluorescente/métodos,
Citometría de Flujo/instrumentación
Abstract Genetic and epigenetic changes have been associated with periodontitis in various genes; however, little is known about genes involved in epigenetic mechanisms and in oxidative stress. Objective: This study aims to investigate the association of polymorphisms C677T in MTHFR (rs1801133) and W...
Estudios de Casos y Controles,
Catalasa/genética,
ADN (Citosina-5-)-Metiltransferasas/genética,
Metilación de ADN/genética,
Estudios de Asociación Genética,
Genotipo,
Metilenotetrahidrofolato Reductasa (NADPH2)/genética,
MicroARNs/genética,
Periodontitis/genética,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético,
Polimorfismo de Longitud del Fragmento de Restricción,
Superóxido Dismutasa-1/genética
This study was initiated to determine whether 2 structurally related flavonoids found in Cyclopia subternata-vicenin-2 (VCN) and scolymoside (SCL)-could modulate renal functional damage in a mouse model of sepsis, and to elucidate the relevant underlying mechanisms. The potential of VCN and SCL treatment...
