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In vitro and in vivo antioxidant potentials of the methanolic crude extract from Inula glomerata Oliv. & Hiern (Asteraceae) and Salacia kraussii (Harv) Harv (Celastraceae)

Ojo, Michael C; Osunsanmi, Foluso O; Cele, Nkosinathi D; Zharare, Godfrey E; Mosa, Rebamang A; Opoku, Andy R.
Bol. latinoam. Caribe plantas med. aromát; 20 (4), 2021
Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo antioxidant potential of the methanolic extracts of Inula glomerata and Salacia kraussii. The plant materials were pulverized and extracted with methan...
Inula/química, Asteraceae/química, Salacia/química, Celastraceae/química, Antioxidantes/química, Antioxidantes/farmacología, Estrés Oxidativo/efectos de los fármacos, Especies Reactivas de Oxígeno, Extractos Vegetales/química, Extractos Vegetales/farmacología, Compuestos Fenólicos/análisis, Flavonoides/análisis, Fitoquímicos/análisis, Óxido Nítrico/metabolismo, Ácidos Sulfónicos/metabolismo, Benzotiazoles/metabolismo, Ratas Sprague-Dawley
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In-vivo Assessment of Antipyretic and Anti-inflammatory Activities of Gymnosporia Royleana Extract in Mice

Khan, H; Khan, I; Khalil, NK; Shahidullah, A; Aziz, A; Khalil, AW; Jan, H; Rahman, IU.
West Indian med. j; 68 (2), 2019
ABSTRACT Objective: Despite the presence of multitude of synthetic drugs against fever and inflammation, none has been proven entirely safe. In contrast, the accepted safety of plant derived natural products is inspiring the world. Based on this fact as well as in view of the diversified activities repo...
Celastraceae/química, Antiinflamatorios/farmacología, Antipiréticos/farmacología, Extractos Vegetales/farmacología, Fiebre/tratamiento farmacológico, Saccharomyces cerevisiae, Fiebre/inducido químicamente, Modelos Animales de Enfermedad, Fitoterapia
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In vivo and in vitro Pharmacological Evaluation of Gymnosporia Royleana

Khan, H; Shad, AA; Khan, I; Aziz, A; Ali, G; Hizbullah, SM; Jan, I.
West Indian med. j; 68 (2), 2019
ABSTRACT Objective: Gymnosporia royleana (G royleana) Wall ex MA Lawson, locally known as (Sur Azghee), is traditionally used for the management of various diseases. In the current investigation, we made an effort to scientifically validate its traditional use in various pathological conditions, such as...
Celastraceae/química, Hipoglucemiantes/farmacología, Antioxidantes/farmacología, Antiinfecciosos/farmacología, Antineoplásicos/farmacología, Extractos Vegetales/farmacología, Hemaglutinación, Modelos Animales de Enfermedad, Diabetes Mellitus/tratamiento farmacológico
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Antibacterial and Antifungal Activities of Compounds Isolated from Gymnosporia Royleana (Celastraceae)

Khan, H; Khan, I; Shah, MR; Shahidullah, A; Khalil, NK; Aziz, A; Khalil, AW; Jan, H; Rahman, IU.
West Indian med. j; 68 (2), 2019
ABSTRACT Objective: In the present study, five new source compounds isolated from aerial parts of Gymnosporia royleana (G royleana) were screened for antibacterial and antifungal activities. Methods: Extraction from plant material was carried out using cold maceration technique. Isolation of pure compo...
Celastraceae/química, Antibacterianos/farmacología, Antifúngicos/farmacología, Extractos Vegetales/farmacología, Extractos Vegetales/aislamiento & purificación, Fitoterapia, Bacterias Grampositivas/efectos de los fármacos, Bacterias Gramnegativas, Candida albicans/efectos de los fármacos, Aspergillus flavus/efectos de los fármacos, Ascomicetos/efectos de los fármacos
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