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Ocotea pulchellaas an alternative against schistosomiasis: chemical analysis, development of nanoemulsion and biological control activity

Passos, Bruno Goulart; Rangel, Leonardo da Silva; Albuquerque, Ricardo Diego Duarte Galhardo de; Caldas, Gabriel Rocha; Santos, Marcelo Guerra; Esteves, Ricardo dos Santos; Milton, Flora Aparecida; Neves, Francisco de Assis Rocha; Ruppelt, Bettina Monika; Santos, José Augusto Albuquerque dos; Faria, Robson Xavier; Rocha, Leandro.
Bol. latinoam. Caribe plantas med. aromát; 19 (5), 2020
The aim of this work was to evaluate the potential of the essential oil (EO) from Ocotea pulchella leaves as an alternative in the control of schistosomiasis. It was tested O. pulchella EO nanoformulation to assess its activity against adult Biomphalaria glabrata, their spawning and Schistossoma mansoni...
Ocotea/química, Aceites Volátiles/administración & dosificación, Aceites Volátiles/química, Moluscos/efectos de los fármacos, Esquistosomiasis/prevención & control, Aceites Volátiles/farmacología, Control Biológico de Vectores, Derivados de Alilbenceno/análisis, Dioxolanos/análisis, Sesquiterpenos de Germacrano/análisis, Monoterpenos Bicíclicos/análisis, Cromatografía de Gases, Emulsiones/administración & dosificación, Emulsiones/farmacología, Interacciones Hidrofóbicas e Hidrofílicas, Biomphalaria/efectos de los fármacos, Cercarias/efectos de los fármacos, Schistosoma mansoni/efectos de los fármacos
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In vivo and in vitro activity of oil extract of garlic (Allium sativum Linnaeus) against Schistosoma japonicum cercariae

Wan, Kang; Wang, Peng; Zhang, Leibo.
Rev. Soc. Bras. Med. Trop; 50 (1), 2017
Abstract: INTRODUCTION: The activity of garlic oil extract against Schistosoma japonicum cercariae was evaluated. METHODS: The in vitro and in vivo cercaricidal activities against S. japonicum larvae were determined. RESULTS: Exposure to ≥ 10-6 (v/v) garlic emulsions for 30 min led to 100% cer...
Cercarias/efectos de los fármacos, Ajo/química, Ratones, Pruebas de Sensibilidad Parasitaria, Extractos Vegetales/farmacología, Schistosoma japonicum/efectos de los fármacos, Factores de Tiempo
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