Analysis of Caspase-9 protein and microRNAs miR-21, miR-126 and miR-155 related to the apoptosis mechanism in the cerebellum of rats submitted to focal cerebral ischemia associated with an alcoholism model
Arq. neuropsiquiatr; 77 (10), 2019
ABSTRACT This study aimed to analyze the cerebellum of rats submitted to an experimental focal cerebral ischemia, by middle cerebral artery occlusion for 90 minutes, followed by reperfusion for 48 hours, associated with an alcoholism model. Methods Fifty adult Wistar rats were used, subdivided into fiv...
Alcoholismo/sangre, Alcoholismo/patología, Apoptosis, Isquemia Encefálica/sangre, Isquemia Encefálica/patología, Caspasa 9/análisis, Cerebelo/química, Cerebelo/patología, Inmunohistoquímica, Infarto de la Arteria Cerebral Media, MicroARNs/sangre, Distribución Aleatoria, Ratas Wistar, Reacción en Cadena en Tiempo Real de la Polimerasa, Daño por Reperfusión/patología, Factores de Tiempo