Quantitation of certolizumab pegol by validated liquid chromatography methods
Braz. J. Pharm. Sci. (Online); 59 (), 2023
Abstract Certolizumab pegol (CZP) is a Fab' fragment of the humanized antibody with anti-TNF-α activity that is indicated as therapy for Crohn's disease and rheumatoid arthritis. Using a BioSep-SEC-S3000 column (300 x 4.6 mm i.d., 5 µm particle size), a size exclusion liquid chromatography (SEC) me...