Studies on the enzymatic specificity of diguanylate cyclases domains and the production of new second messengers
In the first chapter, studies on substrate recognition and enzymatic activity of GGDEF domains are presented. Many proteins containing GGDEF domains are diguanylate cyclases (DGCs, EC 2.7.7.65), enzymes that catalyze the conversion of 2 GTP molecules into the second messenger c-di-GMP in prokaryotes. Thi...
Análisis de Secuencia, Bacillus pumilus/clasificación, Caulobacter crescentus/química, Cianuros/efectos adversos, Cinética, Clonación de Organismos/instrumentación, Concentración de Iones de Hidrógeno, Especificidad por Sustrato, Estilo de Vida, Genoma Bacteriano, Aislamiento de Pacientes, Mutación Puntual