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Radiolabeling of cidofovir with technetium-99m and biodistribution studies

Arribada, Raquel Gregorio; Pereira, Nara Caroline; Cardoso, Valbert Nascimento; Cunha Júnior, Armando da Silva; Barros, André Luís Branco de.
Braz. J. Pharm. Sci. (Online); 56 (), 2020
Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that enables real-time monitoring of the drug. Essays were performed in vitro, showing high radiolabel stability within 24 h. Blood clearance, biodistribution studies, and scintigraphic images were performed in healthy mic...
Cidofovir/farmacología, Atletismo/clasificación, 34628, Métodos, Preparaciones Farmacéuticas/análisis, Riñón, Tiempo de Circulación Sanguínea/efectos adversos, Técnicas In Vitro, Tecnecio/farmacología
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In vitro comparison of acyclovir, ganciclovir and cidofovir against equid alphaherpesvirus 3 and evaluation of their efficacy against six field isolates

Vissani, María A; Zabal, Osvaldo; Tordoya, María S; Parreno, Viviana; Thiry, Etienne; Barrandeguy, María.
Rev. argent. microbiol; 50 (4), 2018
Equid alphaherpesvirus 3 (EHV3) is the etiological agent of equine coital exanthema (ECE), which is a venereal, highly contagious disease, characterized by the formation of papules, vesicles, pustules and ulcers on the external genitalia of mares and stallions. EHV3 remains in a latent state after a succ...
Aciclovir/farmacología, Antivirales/farmacología, Cidofovir/farmacología, Ganciclovir/farmacología, Infecciones por Herpesviridae/veterinaria, Herpesvirus Équido 3/efectos de los fármacos, Enfermedades de los Caballos/virología, Células Cultivadas, Infecciones por Herpesviridae/virología, Herpesvirus Équido 3/aislamiento & purificación, Caballos
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