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DYRK1-mediated phosphorylation of endocytic components is required for extracellular lumen expansion in ascidian notochord

Biol. Res; 56 (), 2023
BACKGROUND: The biological tube is a basal biology structure distributed in all multicellular animals, from worms to humans, and has diverse biological functions. Formation of tubular system is crucial for embryogenesis and adult metabolism. Ascidian Ciona notochord lumen is an excellent in vivo model fo...